Spoligologos: a bioinformatic approach to displaying and analyzing Mycobacterium tuberculosis data

• Published in: Emerging infectious diseases Vol. 8; no. 11; pp. 1306 - 1309
• Main Authors: Driscoll, Jeffrey R, Bifani, Pablo J, Mathema, Barun, McGarry, Michael A, Zickas, Genét M, Kreiswirth, Barry N, Taber, Harry W
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.11.2002; Centers for Disease Control and Prevention
• Subjects: Bacterial Typing Techniques; bioinformatics; Computational Biology - methods; Databases, Factual; Dispatch; DNA Fingerprinting; DNA testing; DNA, Bacterial - analysis; DNA, Bacterial - genetics; DNA, Intergenic - analysis; Evaluation; Genotype; Humans; Mycobacteria; Mycobacterium tuberculosis - genetics; Oligonucleotides - genetics; Polymerase chain reaction; spoligotyping; Tuberculosis; United States; United States

Spacer oligonucleotide (spoligotyping) analysis is a rapid polymerase chain reaction-based method of DNA fingerprinting the Mycobacterium tuberculosis complex. We examined spoligotype data using a bioinformatic tool (sequence logo analysis) to elucidate undisclosed phylogenetic relationships and gai...