Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis

• Published in: Microbiome Vol. 9; no. 1; pp. 1 - 22
• Main Authors: Wu, Zhenhua, Huang, Shimeng, Li, Tiantian, Li, Na, Han, Dandan, Zhang, Bing, Xu, Zhenjiang Zech, Zhang, Shiyi, Pang, Jiaman, Wang, Shilan, Zhang, Guolong, Zhao, Jiangchao, Wang, Junjun
• Format: Journal Article
• Language: English
• Published: London BioMed Central 07.09.2021; BMC
• Subjects: Bacteria; Colitis; Colon; Digestive system; Drinking water; Epigallocatechin gallate; Fatty acids; Fecal microbiota transplantation; Fecal microflora; Feces; Gastrointestinal tract; Green tea; Green tea polyphenol; Gut microbiota; Homeostasis; Inflammatory bowel disease; Inflammatory bowel diseases; Intestinal microflora; Metabolism; Metabolites; Microbiomes; Microbiota; Oral administration; Polyphenols; Prophylaxis; Rectum; Remission; Sterile fecal filtrate; Tea; Transplantation; Transplants & implants; United States > US; Japan; Germany

Background Alteration of the gut microbiota may contribute to the development of inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive constituent of green tea, is known to be beneficial in IBD alleviation. However, it is unclear whether the gut microbiota exerts an...