DNA repair dysregulation from cancer driver to therapeutic target - Curtin, Nicola J. (Nature reviews. Cancer, 2012)
Keywords: 631/337/1427/2566; 692/699/67/1059/602; Analysis; Animals; Antineoplastic Agents - pharmacokinetics; Antineoplastic Agents - pharmacology; Biomarkers - analysis; Biomedical and Life Sciences; Biomedicine; Cancer; Cancer Research; Care and treatment; Cell cycle; Cell Cycle Checkpoints - genetics; Cell survival; Cellular signal transduction; Chemotherapy; Development and progression; DNA Damage; DNA repair; DNA Repair - drug effects; Genetic aspects; Genomics; Homologous Recombination; Humans; Neoplasms - drug therapy; Neoplasms - genetics; Physiological aspects; Radiotherapy; review-article; Signal transduction; Signal Transduction - genetics; Stress; Therapeutic applications