Correlation of Moraxella catarrhalis macrolide susceptibility with the ability to adhere and invade human respiratory epithelial cells

• Published in: Emerging microbes & infections Vol. 11; no. 1; pp. 2055 - 2068
• Main Authors: Liu, Ya-li, Ding, Rui, Jia, Xin-miao, Huang, Jing-jing, Yu, Shuying, Chan, Hiu Tat, Li, Wei, Mao, Lei-li, Zhang, Li, Zhang, Xin-yao, Wu, Wei, Ni, An-ping, Xu, Ying-chun
• Format: Journal Article
• Language: English
• Published: London Taylor & Francis 31.12.2022; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: adhesion; Antibiotics; Cytokines; Genes; Genomes; Hospitals; Infections; invasion; Laboratories; macrolide; Medical research; Medical schools; Moraxella catarrhalis; virulence genes; Mutation; Ontology; pathogenicity; Rare diseases; Virulence

Recently, the prevalence of macrolide-resistant Moraxella catarrhalis has been reported, especially among Chinese children. The fitness cost of resistance is reported to render the resistant bacteria less virulent. To investigate the correlation between macrolide susceptibility of M. catarrhalis and...