Treating HR+/HER2− breast cancer in premenopausal Asian women: Asian Breast Cancer Cooperative Group 2019 Consensus and position on ovarian suppression

• Published in: Breast cancer research and treatment Vol. 177; no. 3; pp. 549 - 559
• Main Authors: Yeo, Winnie, Ueno, Takayuki, Lin, Ching-Hung, Liu, Qiang, Lee, Kyung-Hun, Leung, Roland, Naito, Yoichi, Park, Yeon Hee, Im, Seock-Ah, Li, Huiping, Yap, Yoon Sim, Lu, Yen-Shen
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2019; Springer; Springer Nature B.V
• Subjects: Age Factors; Antineoplastic Agents, Hormonal - administration & dosage; Antineoplastic Agents, Hormonal - adverse effects; Antineoplastic Agents, Hormonal - therapeutic use; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Aromatase; Asian Continental Ancestry Group; Breast cancer; Breast Neoplasms - diagnosis; Breast Neoplasms - drug therapy; Breast Neoplasms - etiology; Cancer; Cancer research; Cancer therapies; Care and treatment; Chemotherapy; Clinical trials; Clinical Trials as Topic; Decision making; Epidermal growth factor; ErbB-2 protein; Evidence-based medicine; Female; Health risk assessment; Humans; Medicine; Medicine & Public Health; Menopause; Neoplasm Grading; Neoplasm Staging; Oncology; Ovarian cancer; Ovariectomy; Patients; Pituitary (anterior); Post-menopause; Postmenopausal women; Premenopause; Receptor, ErbB-2 - genetics; Receptor, ErbB-2 - metabolism; Receptors, Estrogen - genetics; Receptors, Estrogen - metabolism; Receptors, Progesterone - genetics; Receptors, Progesterone - metabolism; Reproductive status; Review; Risk groups; Tamoxifen; Treatment Outcome; Voting; Womens health; Ovarian suppression; Combined endocrine therapy; Treatment; Asia; Premenopausal breast cancer; CDK4/6 inhibitor

Purpose Breast cancer in young Asian women has distinctive clinicopathological characteristics; hence, we question the universal generalizability of treatment recommendations based on data from predominantly non-Asian postmenopausal women. Methods The Asian Breast Cancer Cooperative Group (ABCCG) re...