Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

• Published in: Science (American Association for the Advancement of Science) Vol. 347; no. 6226; pp. 1138 - 1142
• Main Authors: Zeisel, Amit, Muñoz-Manchado, Ana B., Codeluppi, Simone, Lönnerberg, Peter, La Manno, Gioele, Juréus, Anna, Marques, Sueli, Munguba, Hermany, He, Liqun, Betsholtz, Christer, Rolny, Charlotte, Castelo-Branco, Gonçalo, Hjerling-Leffler, Jens, Linnarsson, Sten
• Format: Journal Article
• Language: English
• Published: Washington American Association for the Advancement of Science 06.03.2015; The American Association for the Advancement of Science
• Subjects: Brain; Categories; Cellular; Cellular biology; Cognitive ability; Cortexes; Eyes; Mammals; Ribonucleic acid; Ribonucleic acids; RNA; Rodents; Signatures; Social behavior

The mammalian cerebral cortex supports cognitive functions such as sensorimotor integration, memory, and social behaviors. Normal brain function relies on a diverse set of differentiated cell types, including neurons, glia, and vasculature. Here, we have used large-scale single-cell RNA sequencing (...