Development of nanocubosomes co-loaded with dual anticancer agents curcumin and temozolomide for effective colon cancer therapy

• Published in: Drug delivery Vol. 29; no. 1; pp. 2633 - 2643
• Main Authors: Almoshari, Yosif, Iqbal, Haroon, Razzaq, Anam, Ali Ahmad, Khalil, Khan, Muhammad Khalid, Saeed Alqahtani, Saad, Sultan, Muhammad H., Ali Khan, Barkat
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis 31.12.2022; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Apoptosis; Cancer therapies; colon cancer; Colorectal cancer; curcumin; Nanocubosomes; Particle size; temozolomide; therapy

Current research aimed to develop nanocubosomes co-loaded with dual anticancer drugs curcumin and temozolomide for effective colon cancer therapy. Drugs co-loaded nanocubosomal dispersion was prepared by modified emulsification method using glyceryl monooleate (GMO), pluronic F127 and bovine serum a...