Diagnostic and prognostic utility of tissue factor for severe sepsis and sepsis-induced acute lung injury

• Published in: Journal of translational medicine Vol. 13; no. 1; p. 172
• Main Authors: Xue, Mingming, Sun, Zhan, Shao, Mian, Yin, Jun, Deng, Zhi, Zhang, Jin, Xing, Lingyu, Yang, Xiaoliang, Chen, Bin, Dong, Zhimin, Han, Yi, Sun, Si, Wang, Yuxin, Yao, Chenling, Chu, Xun, Tong, Chaoyang, Song, Zhenju
• Format: Journal Article
• Language: English
• Published: England BioMed Central 30.05.2015
• Subjects: Acute Lung Injury - blood; Acute Lung Injury - etiology; Aged; Case-Control Studies; Female; Humans; Male; Middle Aged; Prognosis; Respiratory Distress Syndrome, Adult - blood; ROC Curve; Sepsis - blood; Sepsis - complications; Sepsis - diagnosis; Survival Analysis; Thromboplastin - metabolism; Treatment Outcome

Tissue factor (TF) and tissue factor pathway inhibitor (TFPI) play a central role in the endothelial permeability regulation and dysfunction, which is associated with the development of sepsis and acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The aim of this study is to assess th...