Linking paternally inherited mtDNA variants and sperm performance

• Published in: Philosophical transactions of the Royal Society of London. Series B. Biological sciences Vol. 375; no. 1790; p. 20190177
• Main Authors: Bettinazzi, Stefano, Nadarajah, Sugahendni, Dalpé, Andréanne, Milani, Liliana, Blier, Pierre U., Breton, Sophie
• Format: Journal Article
• Language: English
• Published: England The Royal Society 20.01.2020
• Subjects: Animals; Bivalvia - genetics; DNA, Mitochondrial - genetics; Genetic Variation; Genotype; Male; Maternal Inheritance; Mercenaria - genetics; Mytilus edulis - genetics; Paternal Inheritance; Spermatozoa - physiology; DUI; OXPHOS; sperm; bivalves; mitochondria; glycolysis

Providing robust links between mitochondrial genotype and phenotype is of major importance given that mitochondrial DNA (mtDNA) variants can affect reproductive success. Because of the strict maternal inheritance (SMI) of mitochondria in animals, haplotypes that negatively affect male fertility can...