Accumulation of cardiolipin and lysocardiolipin in fibroblasts from Tangier disease subjects - Fobker, Manfred; Voss, Reinhard; Reinecke, Holger; Crone, Christina; Assmann, Gerd; Walter, Michael (FEBS letters, 2001)
Keywords: ABCA1, ATP binding cassette transporter 1; Adult; Aged; apo A-I, apolipoprotein A-I; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters - genetics; Biological Transport; Cardiolipin; Cardiolipins - analysis; Cardiolipins - metabolism; Cells, Cultured; Cholesterol - metabolism; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; CL, cardiolipin; DMEM, Dulbecco's modified Eagle's medium; Familial high density lipoprotein deficiency; Female; Fibroblasts - chemistry; Fibroblasts - metabolism; Fibroblasts - pathology; High density lipoprotein; Homozygote; HPLC, high performance liquid chromatography; Humans; LC, lysocardiolipin; Lysocardiolipin; Male; Middle Aged; Niemann–Pick type C disease; NPC disease, Niemann–Pick type C disease; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; Phospholipids - analysis; Phospholipids - metabolism; PI, phosphatidylinositol; PLD, phospholipase D; Sensitivity and Specificity; SM, sphingomyelin; Spectrometry, Mass, Secondary Ion; Sterol trafficking; Tangier disease; Tangier Disease - genetics; Tangier Disease - metabolism; Tangier Disease - pathology; TD, Tangier disease; TLC, thin layer chromatography; TOF SIMS, time-of-flight secondary ion mass spectrometry; NPC disease, Niemann–Pick type C disease; LC, lysocardiolipin; TLC, thin layer chromatography; High density lipoprotein; SM, sphingomyelin; Sterol trafficking; HPLC, high performance liquid chromatography; Lysocardiolipin; ABCA1, ATP binding cassette transporter 1; PI, phosphatidylinositol; PA, phosphatidic acid; PC, phosphatidylcholine; TD, Tangier disease; TOF SIMS, time-of-flight secondary ion mass spectrometry; apo A-I, apolipoprotein A-I; Familial high density lipoprotein deficiency; CL, cardiolipin; PE, phosphatidylethanolamine; ATP binding cassette transporter 1; DMEM, Dulbecco’s modified Eagle’s medium; Apolipoprotein A-I; PLD, phospholipase D; Tangier disease; Cardiolipin; Niemann–Pick type C disease