CYP3A4 drug interactions: correlation of 10 in vitro probe substrates
Aims Many substrates of cytochrome P450 (CYP) 3A4 are used for in vitro investigations of drug metabolism and potential drug–drug interactions. The aim of the present study was to determine the relationship between 10 commonly used CYP3A4 probes using modifiers with a range of inhibitory potency. Me...
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Published in | British journal of clinical pharmacology Vol. 48; no. 5; pp. 716 - 727 |
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Main Authors | , , , |
Format | Journal Article Conference Proceeding |
Language | English |
Published |
Oxford, UK
Blackwell Science Ltd
01.11.1999
Blackwell Science Blackwell Science Inc |
Subjects | |
Online Access | Get full text |
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