Hippocampal Response to a 24-Month Physical Activity Intervention in Sedentary Older Adults

• Published in: The American journal of geriatric psychiatry Vol. 25; no. 3; p. 209
• Main Authors: Rosano, Caterina, Guralnik, Jack, Pahor, Marco, Glynn, Nancy W, Newman, Anne B, Ibrahim, Tamer S, Erickson, Kirk, Cohen, Ronald, Shaaban, C Elizabeth, MacCloud, Rebecca L, Aizenstein, Howard J
• Format: Journal Article
• Language: English
• Published: England 01.03.2017
• Subjects: Aged; Aged, 80 and over; Exercise - physiology; Exercise Therapy - methods; Female; Health Education - methods; Hippocampus - diagnostic imaging; Humans; Magnetic Resonance Imaging; Male; Sedentary Lifestyle; Time Factors; Hippocampal; mobility; ultra high field; physical activity

Greater hippocampal volume is observed in healthy older adults after short-term structured exercise. Whether long-term exposure to real-world physical activity (PA) programs has similar effects for sedentary older adults with impaired mobility and comorbid conditions is not known. A long-term modera...