Persistence of HIV-1 Transmitted Drug Resistance Mutations
There are few data on the persistence of individual human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) mutations in the absence of selective drug pressure. We studied 313 patients in whom TDR mutations were detected at their first resistance test and who had a subsequent t...
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| Published in | The Journal of infectious diseases Vol. 208; no. 9; pp. 1459 - 1463 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Oxford University Press
01.11.2013
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| Subjects | |
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| Abstract | There are few data on the persistence of individual human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) mutations in the absence of selective drug pressure. We studied 313 patients in whom TDR mutations were detected at their first resistance test and who had a subsequent test performed while ART-naive. The rate at which mutations became undetectable was estimated using exponential regression accounting for interval censoring. Most thymidine analogue mutations (TAMs) and T215 revertants (but not T215F/Y) were found to be highly stable, with NNRTI and PI mutations being relatively less persistent. Our estimates are important for informing HIV transmission models. |
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| AbstractList | There are few data on the persistence of individual human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) mutations in the absence of selective drug pressure. We studied 313 patients in whom TDR mutations were detected at their first resistance test and who had a subsequent test performed while ART-naive. The rate at which mutations became undetectable was estimated using exponential regression accounting for interval censoring. Most thymidine analogue mutations (TAMs) and T215 revertants (but not T215F/Y) were found to be highly stable, with NNRTI and PI mutations being relatively less persistent. Our estimates are important for informing HIV transmission models. |
| Author | Castro, Hannah Phillips, Andrew Pillay, Deenan Cane, Patricia Asboe, David Dunn, David T. Cambiano, Valentina |
| AuthorAffiliation | 3 Virus Reference Department , Public Health England , London , United Kingdom 5 Research Department of Infection and Population Health , University College London , London , United Kingdom 1 Medical Research Council Clinical Trials Unit , London , United Kingdom 2 Division of Infection and Immunity , University College London , London , United Kingdom 4 Directorate of HIV Medicine and Sexual Health , Chelsea and Westminster Hospital , London , United Kingdom |
| AuthorAffiliation_xml | – name: 4 Directorate of HIV Medicine and Sexual Health , Chelsea and Westminster Hospital , London , United Kingdom – name: 2 Division of Infection and Immunity , University College London , London , United Kingdom – name: 1 Medical Research Council Clinical Trials Unit , London , United Kingdom – name: 5 Research Department of Infection and Population Health , University College London , London , United Kingdom – name: 3 Virus Reference Department , Public Health England , London , United Kingdom |
| Author_xml | – sequence: 1 givenname: Hannah surname: Castro fullname: Castro, Hannah – sequence: 2 givenname: Deenan surname: Pillay fullname: Pillay, Deenan – sequence: 3 givenname: Patricia surname: Cane fullname: Cane, Patricia – sequence: 4 givenname: David surname: Asboe fullname: Asboe, David – sequence: 5 givenname: Valentina surname: Cambiano fullname: Cambiano, Valentina – sequence: 6 givenname: Andrew surname: Phillips fullname: Phillips, Andrew – sequence: 7 givenname: David T. surname: Dunn fullname: Dunn, David T. |
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| Cites_doi | 10.1086/510533 10.1097/QAI.0b013e3181bca669 10.1097/01.aids.0000131391.91468.ff 10.1016/S1473-3099(11)70032-9 10.1097/QAD.0b013e328344037a 10.1097/QAD.0b013e3280b07761 10.1128/JVI.72.5.3520-3523.1998 10.1038/srep00320 10.1371/journal.pone.0004724 10.1128/JVI.02712-06 10.1093/infdis/jiq167 10.1128/JVI.02579-07 10.1128/JVI.73.5.3744-3752.1999 10.1093/jac/dkr157 10.1177/135965350601100208 |
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| Contributor | Kaye, Steve Hale, Tony Tandy, Richard Greatorex, Jane Rice, Philip Tilston, Peter Smit, Erasmus Hué, Stéphane Pillay, Deenan Cane, Patricia Webster, Daniel Orkin, Chloe Ashton, Lynn Churchill, Duncan Clark, Duncan Kirk, Stuart Templeton, Kate Hay, Phillip Rice, Phillip Collins, Simon Mackie, Nicola Castro, Hannah Payne, Brendan Leigh-Brown, Andrew Delpech, Valerie Goldberg, David Wildfire, Adrian Zhang, Hongyi Chadwick, David Tong, William Geretti, Anna Maria Lazarus, Linda Hale, Antony Bibby, David Aitken, Celia Cox, Alison Mbisa, Tamyo Schmid, Matthias L Asboe, David Williams, Ian Gunson, Rory Paynter, Mary Shepherd, Jill Hopkins, Mark Zuckerman, Mark Fawcett, Tracy Kellam, Paul O'Shea, Siobhan Garcia-Diaz, Ana Mullen, Jane Maclean, Alasdair |
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| Copyright | Copyright © 2013 Oxford University Press on behalf of the Infectious Diseases Society of America 2014 INIST-CNRS The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. 2013 |
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| Keywords | Virus Infection Resistance HIV-1 virus Retroviridae Human immunodeficiency virus Mutation Lentivirus HIV-1 persistence mutations transmitted resistance |
| Language | English |
| License | CC BY 4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| References | van Maarseveen ( key 20180328160231_JIT345C5) 2007; 195 Bezemer ( key 20180328160231_JIT345C6) 2006; 11 Martinez-Picado ( key 20180328160231_JIT345C14) 1999; 73 Wagner ( key 20180328160231_JIT345C12) 2012; 2 Jain ( key 20180328160231_JIT345C2) 2011; 203 Pingen ( key 20180328160231_JIT345C4) 2011; 66 Wittkop ( key 20180328160231_JIT345C1) 2011; 11 Yerly ( key 20180328160231_JIT345C9) 1998; 72 Bennett ( key 20180328160231_JIT345C8) 2009; 4 Little ( key 20180328160231_JIT345C3) 2008; 82 Barbour ( key 20180328160231_JIT345C10) 2004; 18 Cong ( key 20180328160231_JIT345C13) 2006; 81 Varghese ( key 20180328160231_JIT345C15) 2009; 52 Phillips ( key 20180328160231_JIT345C11) 2011; 25 UK Collaborative Group on HIV Drug Resistance ( key 20180328160231_JIT345C7) 2007; 21 |
| References_xml | – volume: 195 start-page: 399 year: 2007 ident: key 20180328160231_JIT345C5 article-title: Persistence of HIV-1 variants with multiple protease inhibitor (PI)-resistance mutations in the absence of PI therapy can be explained by compensatory fixation publication-title: J Infect Dis doi: 10.1086/510533 contributor: fullname: van Maarseveen – volume: 52 start-page: 309 year: 2009 ident: key 20180328160231_JIT345C15 article-title: Minority variants associated with transmitted and acquired HIV-1 nonnucleoside reverse transcriptase inhibitor resistance: implications for the use of second-generation nonnucleoside reverse transcriptase inhibitors publication-title: J Acquir Immune Defic Syndr doi: 10.1097/QAI.0b013e3181bca669 contributor: fullname: Varghese – volume: 18 start-page: 1683 year: 2004 ident: key 20180328160231_JIT345C10 article-title: Persistence of primary drug resistance among recently HIV-1 infected adults publication-title: AIDS doi: 10.1097/01.aids.0000131391.91468.ff contributor: fullname: Barbour – volume: 11 start-page: 363 year: 2011 ident: key 20180328160231_JIT345C1 article-title: Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study publication-title: Lancet Infect Dis doi: 10.1016/S1473-3099(11)70032-9 contributor: fullname: Wittkop – volume: 25 start-page: 843 year: 2011 ident: key 20180328160231_JIT345C11 article-title: Effect on transmission of HIV-1 resistance of timing of implementation of viral load monitoring to determine switches from first to second-line antiretroviral regimens in resource-limited settings publication-title: Aids doi: 10.1097/QAD.0b013e328344037a contributor: fullname: Phillips – volume: 21 start-page: 1035 year: 2007 ident: key 20180328160231_JIT345C7 article-title: Evidence of a decline in transmitted HIV-1 drug resistance in the United Kingdom publication-title: AIDS doi: 10.1097/QAD.0b013e3280b07761 contributor: fullname: UK Collaborative Group on HIV Drug Resistance – volume: 72 start-page: 3520 year: 1998 ident: key 20180328160231_JIT345C9 article-title: Switch to unusual amino acids at Codon 215 of the human immunodeficiency virus type 1 reverse transcriptase gene in seroconvertors infected with zidovudine-resistant variants publication-title: J Virol doi: 10.1128/JVI.72.5.3520-3523.1998 contributor: fullname: Yerly – volume: 2 start-page: 1 year: 2012 ident: key 20180328160231_JIT345C12 article-title: Factors limiting the transmission of HIV mutations conferring drug resistance: fitness costs and genetic bottlenecks publication-title: Sci Rep doi: 10.1038/srep00320 contributor: fullname: Wagner – volume: 4 start-page: e4724 year: 2009 ident: key 20180328160231_JIT345C8 article-title: Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update publication-title: PLoS ONE doi: 10.1371/journal.pone.0004724 contributor: fullname: Bennett – volume: 81 start-page: 3037 year: 2006 ident: key 20180328160231_JIT345C13 article-title: The fitness cost of mutations associated with human immunodeficiency virus type 1 drug resistance is modulated by mutational interactions publication-title: J Virol doi: 10.1128/JVI.02712-06 contributor: fullname: Cong – volume: 203 start-page: 1174 year: 2011 ident: key 20180328160231_JIT345C2 article-title: Differential Persistence of Transmitted HIV-1 Drug Resistance Mutation Classes publication-title: J Infect Dis doi: 10.1093/infdis/jiq167 contributor: fullname: Jain – volume: 82 start-page: 5510 year: 2008 ident: key 20180328160231_JIT345C3 article-title: Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection publication-title: J Virol doi: 10.1128/JVI.02579-07 contributor: fullname: Little – volume: 73 start-page: 3744 year: 1999 ident: key 20180328160231_JIT345C14 article-title: Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1 publication-title: J Virol doi: 10.1128/JVI.73.5.3744-3752.1999 contributor: fullname: Martinez-Picado – volume: 66 start-page: 1467 year: 2011 ident: key 20180328160231_JIT345C4 article-title: Evolutionary pathways of transmitted drug-resistant HIV-1 publication-title: J Antimicrob Chemother doi: 10.1093/jac/dkr157 contributor: fullname: Pingen – volume: 11 start-page: 173 year: 2006 ident: key 20180328160231_JIT345C6 article-title: Evolution of transmitted HIV-1 with drug-resistance mutations in the absence of therapy: effects on CD4+ T-cell count and HIV-1 RNA load publication-title: Antivir Ther doi: 10.1177/135965350601100208 contributor: fullname: Bezemer |
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| SubjectTerms | Adolescent Adult Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Biological and medical sciences Drug resistance Drug Resistance, Viral - genetics Female Fundamental and applied biological sciences. Psychology Genetic mutation HIV HIV 1 HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - genetics HIV/AIDS Hospital units Human immunodeficiency virus 1 Humans Infections Infectious diseases Major and Brief Reports Male Medical sciences Memory interference Microbiology Miscellaneous Teaching hospitals Virology Viruses Young Adult |
| Title | Persistence of HIV-1 Transmitted Drug Resistance Mutations |
| URI | https://www.jstor.org/stable/42580592 https://www.ncbi.nlm.nih.gov/pubmed/23904291 https://search.proquest.com/docview/1443385183 https://search.proquest.com/docview/1654689367 https://pubmed.ncbi.nlm.nih.gov/PMC3789571 |
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