The Isoenzymic Diketocamphane Monooxygenases of Pseudomonas putida ATCC 17453—An Episodic History and Still Mysterious after 60 Years

• Published in: Microorganisms (Basel) Vol. 9; no. 12; p. 2593
• Main Author: Willetts, Andrew
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15.12.2021; MDPI
• Subjects: active sites; biocatalysts; Biochemistry; Camphor; Camphor 5-monooxygenase; catabolism; Cell culture; diketocamphane monooxygenase; Enzymes; Equivalence; ferric-flavin reductase; Flavin; flavin-dependent two-component monooxygenases; Flavoproteins; ketolactonase; mechanism of action; Mode of action; Oxidation; Oxygen; Peracids; Prostheses; Pseudomonas putida; putidaredoxin reductase; Review; Steroids; United States > US; Illinois; ferric-flavin reductase; putidaredoxin reductase; diketocamphane monooxygenase; flavin-dependent two-component monooxygenases; ketolactonase

Researching the involvement of molecular oxygen in the degradation of the naturally occurring bicyclic terpene camphor has generated a six-decade history of fascinating monooxygenase biochemistry. While an extensive bibliography exists reporting the many varied studies on camphor 5-monooxygenase, th...