Manganese supplementation increases adiponectin and lowers ICAM-1 and creatinine blood levels in Zucker type 2 diabetic rats, and downregulates ICAM-1 by upregulating adiponectin multimerization protein (DsbA-L) in endothelial cells - Burlet, Elodie; Jain, Sushil K. (Molecular and cellular biochemistry, 2017)
Keywords: 3T3-L1 Cells; Adiponectin - metabolism; Animals; Atherosclerosis; Biochemistry; Biomedical and Life Sciences; Blood; Cardiology; Cells; Cellular biology; Creatinine - blood; Diabetes; Diabetes Mellitus, Experimental - diet therapy; Diabetes Mellitus, Experimental - metabolism; Diabetes Mellitus, Type 2 - diet therapy; Diabetes Mellitus, Type 2 - metabolism; Dietary Supplements; Down-Regulation; Endothelial Cells - drug effects; Endothelium; Gene Expression Regulation - drug effects; Glucose; Glutathione Transferase - metabolism; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1 - metabolism; Life Sciences; Male; Manganese; Manganese - administration & dosage; Manganese - pharmacology; Manganese compounds; Medical Biochemistry; Mice; Oncology; Oxidases; Oxidative stress; Oxidative Stress - drug effects; Protein binding; Proteins; Rats; Rats, Zucker; Rodents; Type 2 diabetes; Up-Regulation; ICAM-1; Diabetes; DsbA-L; Manganese; Adiponectin