Differences in Cytokine Production in Human Macrophages and in Virulence in Mice Are Attributable to the Acidic Polymerase Protein of Highly Pathogenic Influenza A Virus Subtype H5N1 - Sakabe, Saori; Takano, Ryo; Nagamura-Inoue, Tokiko; Yamashita, Naohide; Nidom, Chairul A.; Mai thi Quynh Le; Iwatsuki-Horimoto, Kiyoko; Kawaoka, Yoshihiro (The Journal of infectious diseases, 2013)
Keywords: Animals; Biological and medical sciences; Cytokines; Cytokines - biosynthesis; Cytokines - immunology; Epithelial cells; Epithelial Cells - immunology; Epithelial Cells - virology; Female; Fundamental and applied biological sciences. Psychology; Genes; H5N1 subtype influenza A virus; HEK293 Cells; Human growth; Humans; Infections; Infectious diseases; Influenza; Influenza A virus; Influenza A Virus, H5N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza A Virus, H5N1 Subtype - physiology; Influenza, Human - immunology; Influenza, Human - virology; Macrophages; Macrophages - immunology; Macrophages - virology; Madin Darby Canine Kidney Cells; Major and Brief Reports; Medical sciences; Mice; Mice, Inbred BALB C; Microbiology; Orthomyxoviridae Infections - immunology; Orthomyxoviridae Infections - veterinary; Orthomyxoviridae Infections - virology; Reassortant Viruses - genetics; Reassortant Viruses - metabolism; Reassortant Viruses - pathogenicity; RNA Replicase - genetics; Viral Proteins - genetics; Virulence; Virulence - genetics; Viruses; Human; Infection; Influenzavirus A(H5N1); Vertebrata; Mammalia; Mouse; Acidic protein; Virulence; Rodentia; Cytokine; Subtype; Macrophage