Craving in Alcohol-Dependent Patients After Detoxification Is Related to Glutamatergic Dysfunction in the Nucleus Accumbens and the Anterior Cingulate Cortex - Bauer, Jochen; Pedersen, Anya; Scherbaum, Norbert; Bening, Johanna; Patschke, Johanna; Kugel, Harald; Heindel, Walter; Arolt, Volker; Ohrmann, Patricia (Neuropsychopharmacology (New York, N.Y.), 2013)
Keywords: Abstinence; Addictive behaviors; Adult; Adult and adolescent clinical studies; Alcoholism; Alcoholism - diagnosis; Alcoholism - metabolism; Alcoholism - therapy; Alcoholism and acute alcohol poisoning; Behavior, Addictive - diagnosis; Behavior, Addictive - metabolism; Behavior, Addictive - therapy; Biological and medical sciences; Brain; Desintoxication. Drug withdrawal; Drug withdrawal; Ethanol; Female; Glutamic Acid - metabolism; Gyrus Cinguli - metabolism; Humans; Hypotheses; Magnetic Resonance Spectroscopy - methods; Male; Medical sciences; Metabolism; Metabolites; Middle Aged; Nucleus Accumbens - metabolism; Original; Physiology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Spectrum analysis; Substance Withdrawal Syndrome - diagnosis; Substance Withdrawal Syndrome - metabolism; Substance Withdrawal Syndrome - therapy; Surveys and Questionnaires; Toxicology; Treatments; Germany; Human; Poison withdrawal; Alcoholism; Craving; Central nervous system; Detoxification; Basal ganglion; withdrawal; Glutamate; Encephalon; Nucleus accumbens; H MRS; Alcoholic beverage; Cingulate cortex; Dependence; Excitatory aminoacid; Neurotransmitter; Disintoxication