LightDock: a new multi-scale approach to protein-protein docking

• Published in: Bioinformatics Vol. 34; no. 1; pp. 49 - 55
• Main Authors: Jiménez-García, Brian, Roel-Touris, Jorge, Romero-Durana, Miguel, Vidal, Miquel, Jiménez-González, Daniel, Fernández-Recio, Juan
• Format: Journal Article Publication
• Language: English
• Published: England Oxford University Press 01.01.2018
• Subjects: Aplicacions de la informàtica; Bioinformàtica; Informàtica; Investigació; Protein research; Proteïnes; Àrees temàtiques de la UPC

Abstract Motivation Computational prediction of protein-protein complex structure by docking can provide structural and mechanistic insights for protein interactions of biomedical interest. However, current methods struggle with difficult cases, such as those involving flexible proteins, low-affinit...