Computer-aided diagnosis of pulmonary diseases using x-ray darkfield radiography

• Published in: Physics in medicine & biology Vol. 60; no. 24; pp. 9253 - 9268
• Main Authors: Einarsdóttir, Hildur, Yaroshenko, Andre, Velroyen, Astrid, Bech, Martin, Hellbach, Katharina, Auweter, Sigrid, Yildirim, Önder, Meinel, Felix G, Eickelberg, Oliver, Reiser, Maximilian, Larsen, Rasmus, Ersbøll, Bjarne Kjær, Pfeiffer, Franz
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 21.12.2015
• Subjects: active appearance model; Animals; Case-Control Studies; Clinical Medicine; dark-field imaging; Diagnosis, Computer-Assisted - methods; Grating based interferometry; Humans; Image Processing, Computer-Assisted - methods; Klinisk medicin; Lung - diagnostic imaging; lung segmentation; Medical and Health Sciences; Medicin och hälsovetenskap; Mice; pulmonary disease; Pulmonary Emphysema - diagnostic imaging; Pulmonary Fibrosis - diagnostic imaging; Radiography, Thoracic; Radiologi och bildbehandling; Radiology and Medical Imaging; Radiology, Nuclear Medicine and Medical Imaging; Sensitivity and Specificity; X-ray radiography; X-Rays

In this work we develop a computer-aided diagnosis (CAD) scheme for classification of pulmonary disease for grating-based x-ray radiography. In addition to conventional transmission radiography, the grating-based technique provides a dark-field imaging modality, which utilizes the scattering propert...