Initial Surgical Versus Conservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis

• Published in: Journal of the American College of Cardiology Vol. 66; no. 25; pp. 2827 - 2838
• Main Authors: Taniguchi, Tomohiko, MD, Morimoto, Takeshi, MD, MPH, Shiomi, Hiroki, MD, Ando, Kenji, MD, Kanamori, Norio, MD, Murata, Koichiro, MD, Kitai, Takeshi, MD, Kawase, Yuichi, MD, Izumi, Chisato, MD, Miyake, Makoto, MD, Mitsuoka, Hirokazu, MD, Kato, Masashi, MD, Hirano, Yutaka, MD, Matsuda, Shintaro, MD, Nagao, Kazuya, MD, Inada, Tsukasa, MD, Murakami, Tomoyuki, MD, Takeuchi, Yasuyo, MD, Yamane, Keiichiro, MD, Toyofuku, Mamoru, MD, Ishii, Mitsuru, MD, Minamino-Muta, Eri, MD, Kato, Takao, MD, Inoko, Moriaki, MD, Ikeda, Tomoyuki, MD, Komasa, Akihiro, MD, Ishii, Katsuhisa, MD, Hotta, Kozo, MD, Higashitani, Nobuya, MD, Kato, Yoshihiro, MD, Inuzuka, Yasutaka, MD, Maeda, Chiyo, MD, Jinnai, Toshikazu, MD, Morikami, Yuko, MD, Sakata, Ryuzo, MD, Kimura, Takeshi, MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 29.12.2015; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; aortic valve replacement; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - therapy; Cardiology; Cardiovascular; Clinical outcomes; Echocardiography; Female; Follow-Up Studies; Heart attacks; Heart Valve Prosthesis Implantation - standards; Hospitalization; Humans; Internal Medicine; Male; Mortality; Practice Guidelines as Topic; Propensity Score; propensity-matched; Registries; registry; risk; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; watchful waiting; Watchful Waiting - standards; registry; heart failure; peak aortic jet velocity; aortic valve replacement; LVEF; IQR; interquartile range; AVA; propensity-matched; left ventricular ejection fraction; pressure gradient; AS; aortic stenosis; STS; V max; PG; Society of Thoracic Surgeons; risk; aortic valve area; AVR; watchful waiting; HF; Vmax

Abstract Background Current guidelines generally recommend watchful waiting until symptoms emerge for aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis (AS). Objectives The study sought to compare the long-term outcomes of initial AVR versus conservative strategies...