Combinational strategy for high-performance cancer chemotherapy

• Published in: Biomaterials Vol. 171; pp. 178 - 197
• Main Authors: Qin, Si-Yong, Cheng, Yin-Jia, Lei, Qi, Zhang, Ai-Qing, Zhang, Xian-Zheng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.07.2018
• Subjects: Antineoplastic Agents - therapeutic use; Cancer therapy; Combinational mechanism; Combined Modality Therapy; drugs; gene therapy; Genetic Therapy; guidelines; Humans; Immunotherapy; Multidrug resistance (MDR); neoplasms; Neoplasms - drug therapy; Neoplasms - immunology; Phototherapy; signal transduction; surveys; Therapeutic effect; Multidrug resistance (MDR); Combinational mechanism; Cancer therapy; Therapeutic effect

The clinical outcomes of conventional mono-chemotherapy of cancers are usually far from satisfactory due to some issues such as tumor heterogeneity and resistance to chemotherapeutic drugs. With the increasing knowledge of molecular signal pathways and pathological mechanisms involved in the initiat...