Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum - Hulbert, Alicia; Jusue-Torres, Ignacio; Stark, Alejandro; Chen, Chen; Rodgers, Kristen; Lee, Beverly; Griffin, Candace; Yang, Andrew; Huang, Peng; Wrangle, John; Belinsky, Steven A.; Wang, Tza-Huei; et al. (Clinical cancer research, 2017)
Keywords: Aged; Area Under Curve; Beads; Biomarkers, Tumor - analysis; Biomarkers, Tumor - genetics; Cancer; Cancer screening; Carcinoma, Non-Small-Cell Lung - blood; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - genetics; Case-Control Studies; Computed tomography; Confidence intervals; Deoxyribonucleic acid; Diagnostic systems; DNA; DNA - analysis; DNA methylation; DNA Methylation - genetics; Early Detection of Cancer - methods; Experimental design; Female; Gene Expression Profiling - methods; Genes; Humans; Lung cancer; Lung Neoplasms - blood; Lung Neoplasms - diagnosis; Lung Neoplasms - genetics; Male; Medical screening; Middle Aged; Nodules; Plasma; Prediction models; Promoter Regions, Genetic - genetics; Real-Time Polymerase Chain Reaction; ROC Curve; Sensitivity; Sensitivity and Specificity; Sputum; Sputum - chemistry; Transcriptome