Impact of blood rheology on wall shear stress in a model of the middle cerebral artery

• Published in: Interface focus Vol. 3; no. 2; p. 20120094
• Main Authors: Bernabeu, Miguel O., Nash, Rupert W., Groen, Derek, Carver, Hywel B., Hetherington, James, Krüger, Timm, Coveney, Peter V.
• Format: Journal Article
• Language: English
• Published: England The Royal Society 06.04.2013
• Subjects: Blood Flow Modelling; Lattice Boltzmann; Multi-Scale Modelling; Rheology; Three-Band Diagram Analysis; lattice Boltzmann; blood flow modelling; three-band diagram analysis; rheology; multi-scale modelling

Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies, including intracranial aneurysms and atherosclerosis. Recent computational work suggests that, in order to correctly characterize such forces,...