Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma - Allam, Venkata Sita Rama Raju; Montpeyó, David; Beau, Fabrice; Taha, Sowsan; Waern, Ida; Akula, Srinivas; Avilés, Francesc Xavier; Lorenzo, Julia; Devel, Laurent; Pejler, Gunnar; Wernersson, Sara (Inflammation research, 2025)
Keywords: Allergology; Animals; Anti-Asthmatic Agents - pharmacology; Anti-Asthmatic Agents - therapeutic use; Asthma; Asthma - drug therapy; Asthma - immunology; Asthma - pathology; Autoimmunitet och inflammation; Autoimmunity and Inflammation; Bioengineering; Biomedical and Life Sciences; Biomedicine; Carboxypeptidase; Carboxypeptidase A; Carboxypeptidase B; Carboxypeptidases A - antagonists & inhibitors; Dermatology; Disease Models, Animal; Dust; Female; Gene expression; Histopathology; House dust; House dust mite; Immunology; Inflammation; Inhibitors; Life Sciences; Lung - drug effects; Lung - immunology; Lung - pathology; Lungs; Metallography; Mice; Mice, Inbred BALB C; Mites; Neurology; Pharmacology/Toxicology; Pyroglyphidae - immunology; Respiratory tract diseases; Rheumatology; Smooth muscle; Therapeutic applications; Therapeutic targets; Inflammation; Carboxypeptidase; House dust mite; Asthma