Effect of gravity and microgravity on intracranial pressure

• Published in: The Journal of physiology Vol. 595; no. 6; pp. 2115 - 2127
• Main Authors: Lawley, Justin S., Petersen, Lonnie G., Howden, Erin J., Sarma, Satyam, Cornwell, William K., Zhang, Rong, Whitworth, Louis A., Williams, Michael A., Levine, Benjamin D.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 15.03.2017; John Wiley and Sons Inc
• Subjects: Adult; bedrest; Central Venous Pressure; Female; Humans; idiopathic intracranial hypertension; Integrative; Integrative Physiology; Intracranial Pressure; Male; Middle Aged; ocular remodeling; Posture; Research Paper; space; Space Flight; Weightlessness; Young Adult; idiopathic intracranial hypertension; posture; ocular remodeling; space; bedrest

Key Points Astronauts have recently been discovered to have impaired vision, with a presentation that resembles syndromes of elevated intracranial pressure on Earth. Gravity has a profound effect on fluid distribution and pressure within the human circulation. In contrast to prevailing theory, we ob...