Biological clocks and incremental growth line formation in dentine

• Published in: Journal of Anatomy Vol. 237; no. 2; pp. 367 - 378
• Main Authors: Papakyrikos, Amanda M., Arora, Manish, Austin, Christine, Boughner, Julia C., Capellini, Terence D., Dingwall, Heather L., Greba, Quentin, Howland, John G., Kato, Akiko, Wang, Xiu‐Ping, Smith, Tanya M.
• Format: Journal Article
• Language: English
• Published: England Wiley 01.08.2020; Wiley Subscription Services, Inc; John Wiley and Sons Inc
• Subjects: Animals; ARNTL Transcription Factors; ARNTL Transcription Factors - genetics; Biological Clocks; Biological Clocks - genetics; biological rhythm; Bmal1; BMAL1 protein; Circadian Rhythm; Circadian Rhythm - genetics; Circadian rhythms; Clock gene; dental development; Dental enamel; Dental roots; Dentin; Dentin - growth & development; Enamel; Genotypes; Growth rate; incremental feature; Mice; Mice, Knockout; Original; Rats; Rats, Wistar; Rhythm; subdaily rhythm; Suprachiasmatic nucleus; ultradian rhythm; ultradian rhythm; dental development; circadian rhythm; enamel; incremental feature; subdaily rhythm; suprachiasmatic nucleus; clock gene; Bmal1; biological rhythm

Dentine‐ and enamel‐forming cells secrete matrix in consistent rhythmic phases, resulting in the formation of successive microscopic growth lines inside tooth crowns and roots. Experimental studies of various mammals have proven that these lines are laid down in subdaily, daily (circadian), and mult...