Individual Airway Closure Characterized In Vivo by Phase-Contrast CT Imaging in Injured Rabbit Lung

• Published in: Critical care medicine Vol. 47; no. 9; p. e774
• Main Authors: Broche, Ludovic, Pisa, Pauline, Porra, Liisa, Degrugilliers, Loïc, Bravin, Alberto, Pellegrini, Mariangela, Borges, João Batista, Perchiazzi, Gaetano, Larsson, Anders, Hedenstierna, Göran, Bayat, Sam
• Format: Journal Article
• Language: English
• Published: United States 01.09.2019
• Subjects: Airway Obstruction - diagnostic imaging; Animals; Lung - diagnostic imaging; Lung - physiopathology; Rabbits; Respiration, Artificial - adverse effects; Tomography, X-Ray Computed

Airway closure is involved in adverse effects of mechanical ventilation under both general anesthesia and in acute respiratory distress syndrome patients. However, direct evidence and characterization of individual airway closure is lacking. Here, we studied the same individual peripheral airways in...