Long Noncoding RNAs as Novel Biomarkers Have a Promising Future in Cancer Diagnostics

• Published in: Disease markers Vol. 2016; no. 2016; pp. 1 - 10
• Main Authors: Shi, Ting, Cao, Yingli, Gao, Ge
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2016; John Wiley & Sons, Inc
• Subjects: Biological markers; Biomarkers, Tumor - blood; Biomarkers, Tumor - genetics; Biomarkers, Tumor - urine; Cancer; Diagnosis; Early Detection of Cancer; Gastric Juice - chemistry; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Health aspects; Humans; Molecular Diagnostic Techniques - standards; Neoplasms - diagnosis; Neoplasms - genetics; Practice Guidelines as Topic; Review; RNA; RNA, Long Noncoding - blood; RNA, Long Noncoding - genetics; RNA, Long Noncoding - urine; Saliva - chemistry

Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are involved in tumorigenesis, tumor cells proliferation, invasion, migration, apoptosis, and angiogenesis. Furthermore, extracel...