Current and future perspectives on the regulation and functions of miR-545 in cancer development

• Published in: Cancer pathogenesis and therapy Vol. 2; no. 3; pp. 142 - 154
• Main Authors: Shen, Jinze, Su, Xinming, Wang, Qurui, Ke, Yufei, Zheng, Tianyu, Mao, Yunan, Wang, Zehua, Dong, Jingyin, Duan, Shiwei
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2024; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Elsevier
• Subjects: Biomarker; Cell behavior; Competing endogenous RNA; Immunotherapy; miR-545; Review; Therapeutic drug; Biomarker; Therapeutic drug; miR-545; Cell behavior; Immunotherapy; Competing endogenous RNA

Micro ribonucleic acids (miRNAs) are a highly conserved class of single-stranded non-coding RNAs. Within the miR-545/374a cluster, miR-545 resides in the intron of the long non-coding RNA (lncRNA) FTX on Xq13.2. The precursor form, pre-miR-545, is cleaved to generate two mature miRNAs, miR-545-3p an...