Medication adherence interventions that target subjects with adherence problems: Systematic review and meta-analysis

Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions...

Full description

Saved in:
Bibliographic Details
Published inResearch in social and administrative pharmacy Vol. 12; no. 2; pp. 218 - 246
Main Authors Conn, Vicki S., Ruppar, Todd M., Enriquez, Maithe, Cooper, Pam
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2016
Subjects
Clinical Trials as Topic
Humans
Intervention
Medication Adherence
Meta-analysis
Systematic review
Medication adherence
Intervention
Systematic review
Meta-analysis
Online AccessGet full text

Cover

Abstract Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties. This systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties. Primary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics. Data were extracted from 53 reports of studies involving 8243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found for interventions that linked medication taking with existing habits compared to interventions that did not (0.574 vs. 0.222). Effect sizes were largest among studies that measured adherence by pill counts or electronic event monitoring systems. Analysis of study design features identified several potential risks of bias. Statistically significant publication bias was detected, but adherence effect sizes were not significantly associated with other risks of bias. These findings document that interventions targeting individuals with medication adherence problems can have modest but significant effects on medication-taking behavior. The findings support the use of behavioral strategies such as prompts and linking medications to habits to increase medication adherence in adults with adherence challenges. Face-to-face interventions appear to be critical for patients who have experienced past problems with medication adherence.
AbstractList Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties. This systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties. Primary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics. Data were extracted from 53 reports of studies involving 8243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found for interventions that linked medication taking with existing habits compared to interventions that did not (0.574 vs. 0.222). Effect sizes were largest among studies that measured adherence by pill counts or electronic event monitoring systems. Analysis of study design features identified several potential risks of bias. Statistically significant publication bias was detected, but adherence effect sizes were not significantly associated with other risks of bias. These findings document that interventions targeting individuals with medication adherence problems can have modest but significant effects on medication-taking behavior. The findings support the use of behavioral strategies such as prompts and linking medications to habits to increase medication adherence in adults with adherence challenges. Face-to-face interventions appear to be critical for patients who have experienced past problems with medication adherence.
Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties.BACKGROUNDInadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties.This systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties.OBJECTIVEThis systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties.Primary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics.METHODSPrimary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics.Data were extracted from 53 reports of studies involving 8243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found for interventions that linked medication taking with existing habits compared to interventions that did not (0.574 vs. 0.222). Effect sizes were largest among studies that measured adherence by pill counts or electronic event monitoring systems. Analysis of study design features identified several potential risks of bias. Statistically significant publication bias was detected, but adherence effect sizes were not significantly associated with other risks of bias.RESULTSData were extracted from 53 reports of studies involving 8243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found for interventions that linked medication taking with existing habits compared to interventions that did not (0.574 vs. 0.222). Effect sizes were largest among studies that measured adherence by pill counts or electronic event monitoring systems. Analysis of study design features identified several potential risks of bias. Statistically significant publication bias was detected, but adherence effect sizes were not significantly associated with other risks of bias.These findings document that interventions targeting individuals with medication adherence problems can have modest but significant effects on medication-taking behavior. The findings support the use of behavioral strategies such as prompts and linking medications to habits to increase medication adherence in adults with adherence challenges. Face-to-face interventions appear to be critical for patients who have experienced past problems with medication adherence.CONCLUSIONSThese findings document that interventions targeting individuals with medication adherence problems can have modest but significant effects on medication-taking behavior. The findings support the use of behavioral strategies such as prompts and linking medications to habits to increase medication adherence in adults with adherence challenges. Face-to-face interventions appear to be critical for patients who have experienced past problems with medication adherence.
Author Enriquez, Maithe
Cooper, Pam
Conn, Vicki S.
Ruppar, Todd M.
AuthorAffiliation a Sinclair School of Nursing; University of Missouri; Columbia, MO 65211; USA
AuthorAffiliation_xml – name: a Sinclair School of Nursing; University of Missouri; Columbia, MO 65211; USA
Author_xml – sequence: 1
  givenname: Vicki S.
  surname: Conn
  fullname: Conn, Vicki S.
  email: conn@missouri.edu
– sequence: 2
  givenname: Todd M.
  surname: Ruppar
  fullname: Ruppar, Todd M.
– sequence: 3
  givenname: Maithe
  orcidid: 0000-0003-2754-4019
  surname: Enriquez
  fullname: Enriquez, Maithe
– sequence: 4
  givenname: Pam
  surname: Cooper
  fullname: Cooper, Pam
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26164400$$D View this record in MEDLINE/PubMed
BookMark eNqFkV-P1CAUxYlZ4_7Rj6Dh0ZdWaCm0mmjMxl1N1vigPpNbertl0sIIzGzm28s4s2b1ZUMIN3DPOeH-zsmJ8w4JeclZyRmXb1ZlhPUEYSkrxpuSyZIx_oSc8a4WRcsbdpLrpuGFEpyfkvMYV4zVinHxjJxWkkshGDsj6SsO1kCy3lEYJgzoDFLrEoYtuv11pGmCRBOEW0w0bvoVmhTpnU3TA8U6-H7GJb6l33cx4ZIdDQ24tXhHwQ10wQQFOJh30cbn5OkIc8QXx_OC_Lz69OPyc3Hz7frL5cebwjS1SkVv6j7vUQwMVFdD1_diHIHXXSWgNuOoZG9YZ4wA044DU6ptK2TY9K0wajT1BXl_8F1v-gUHkz8UYNbrYBcIO-3B6n9fnJ30rd9qIVWnqjYbvD4aBP9rgzHpxUaD8wwO_SZqrmTVySqv3PrqYdbfkPtR54Z3hwYTfIwBR21s-jP4HG1nzZneg9UrfQSr92A1kzqDzermP_V9wGO6Dwcd5jlnGkFHY_fEBhsyRz14-4jDb3syxag
CitedBy_id crossref_primary_10_1080_10410236_2022_2131973
crossref_primary_10_1111_jocn_16589
crossref_primary_10_5812_semj_135491
crossref_primary_10_1080_17437199_2022_2034516
crossref_primary_10_1002_hec_3804
crossref_primary_10_1080_17437199_2020_1806722
crossref_primary_10_1177_0894318420921155
crossref_primary_10_1186_s12875_019_1016_6
crossref_primary_10_1177_2325958219838858
crossref_primary_10_1093_abm_kaac010
crossref_primary_10_1186_s12913_022_08243_4
crossref_primary_10_1007_s11606_016_3927_4
crossref_primary_10_25207_1608_6228_2021_28_4_100_117
crossref_primary_10_1007_s40266_016_0433_7
crossref_primary_10_1016_j_sapharm_2020_03_002
crossref_primary_10_3928_00989134_20170523_01
crossref_primary_10_2196_38073
crossref_primary_10_2147_PPA_S249079
crossref_primary_10_1176_appi_prcp_20210021
crossref_primary_10_26416_Farm_213_4_2023_8585
crossref_primary_10_3389_fphar_2018_01454
crossref_primary_10_1136_bmjopen_2019_036526
crossref_primary_10_1111_imj_13687
crossref_primary_10_1186_s12936_024_05057_z
crossref_primary_10_1186_s12913_025_12461_x
crossref_primary_10_1136_ejhpharm_2021_002903
crossref_primary_10_1080_09540121_2020_1771263
crossref_primary_10_1016_j_pedn_2024_10_009
crossref_primary_10_1155_2020_7650915
crossref_primary_10_7759_cureus_47756
crossref_primary_10_1007_s11096_021_01270_x
crossref_primary_10_1371_journal_pone_0255478
crossref_primary_10_1016_j_mcna_2016_08_005
crossref_primary_10_3390_children10091449
crossref_primary_10_1080_13651501_2020_1782434
crossref_primary_10_1186_s12909_025_06909_1
crossref_primary_10_2196_25175
crossref_primary_10_3390_ijerph16203797
crossref_primary_10_1111_jep_12773
crossref_primary_10_1007_s10461_018_2353_5
crossref_primary_10_1016_j_ijnurstu_2021_103975
crossref_primary_10_1111_jocn_16936
crossref_primary_10_1371_journal_pone_0304897
crossref_primary_10_4236_psych_2022_1311102
crossref_primary_10_1108_JSM_01_2023_0023
crossref_primary_10_18553_jmcp_2016_22_11_1247
crossref_primary_10_1016_j_pec_2019_07_019
crossref_primary_10_1136_bmjopen_2024_084492
crossref_primary_10_1136_bmjopen_2023_072502
crossref_primary_10_1080_14737167_2023_2161516
crossref_primary_10_1007_s11906_015_0606_5
crossref_primary_10_1016_j_sapharm_2018_02_002
crossref_primary_10_26416_Farm_218_3_2024_10050
crossref_primary_10_1093_ajhp_zxz284
crossref_primary_10_1016_j_aohep_2022_100748
crossref_primary_10_1177_2042098618764536
crossref_primary_10_2147_PPA_S393749
crossref_primary_10_1007_s11886_023_01960_0
crossref_primary_10_1097_MPG_0000000000003885
crossref_primary_10_1109_MPRV_2020_2993993
crossref_primary_10_1111_bjhp_12458
crossref_primary_10_1111_bjhp_12579
crossref_primary_10_1177_23259582241236260
crossref_primary_10_2196_47473
crossref_primary_10_1111_jch_13071
crossref_primary_10_2147_PPA_S302818
crossref_primary_10_1177_2150131915601794
crossref_primary_10_11124_JBISRIR_2017_003971
crossref_primary_10_1080_08870446_2022_2144923
crossref_primary_10_1145_3719347
crossref_primary_10_1007_s10865_016_9730_1
crossref_primary_10_1080_15412555_2020_1833852
crossref_primary_10_1136_bmjhci_2021_100540
crossref_primary_10_1186_s12889_024_18081_0
crossref_primary_10_1186_s12939_022_01699_0
crossref_primary_10_3389_fneur_2024_1462478
crossref_primary_10_1007_s40271_019_00377_8
crossref_primary_10_3390_healthcare8040487
crossref_primary_10_3928_00989134_20190212_01
crossref_primary_10_1007_s10916_024_02135_2
crossref_primary_10_1111_2047_3095_12210
crossref_primary_10_2196_10421
crossref_primary_10_1177_1474515120938235
crossref_primary_10_1007_s11096_025_01885_4
crossref_primary_10_1111_ctr_13353
crossref_primary_10_1080_17437199_2022_2127831
crossref_primary_10_1016_j_nurpra_2023_104791
crossref_primary_10_1097_JNC_0000000000000059
crossref_primary_10_3389_fpsyg_2017_01769
crossref_primary_10_1002_pbc_28216
crossref_primary_10_3389_fdgth_2025_1467772
Cites_doi 10.1080/09540120310001618630
10.1093/geront/gnp037
10.1136/bmj.315.7109.640
10.1007/s00125-007-0625-0
10.1177/1094428106287393
10.1016/j.ijmedinf.2012.05.005
10.1136/bmj.38905.447118.2F
10.1016/j.pec.2009.03.022
10.1097/00006199-200307000-00008
10.1002/sim.4780110307
10.1097/01.aids.0000168975.44219.45
10.1016/j.jclinepi.2009.06.006
10.1097/00005650-200209000-00009
10.1111/j.1440-172X.1997.tb00104.x
10.1177/0002716202250791
10.1037/1082-989X.3.4.486
10.1016/S0149-2918(02)85026-3
10.1080/09540121.2011.579945
10.1089/apc.2006.0028
10.1001/jama.1995.03530240072044
10.1097/01.mlr.0000115957.44388.7c
10.1016/S0196-0644(99)70268-4
10.1001/archpedi.152.8.812
10.1038/jhh.2010.133
10.1016/S1077-7229(04)80058-0
10.1097/01.qai.0000197870.99196.ea
10.1080/0954012021000039833
10.1111/j.1464-5491.2010.03133.x
10.1136/bmj.309.6964.1286
10.1300/J115v10n02_04
10.1207/S15324796ABM2403_04
10.1016/j.pec.2007.10.004
10.1016/S0140-6736(02)07942-4
10.1002/bjs.6302
10.7748/nr2000.04.7.3.40.c6120
10.1002/nur.10092
10.1001/jama.287.21.2829
10.1093/ajhp/60.24.2593
10.1016/S0140-6736(76)91737-2
10.1017/S0266462300103150
10.1177/0193945911427153
10.1177/1055329002238026
10.1186/1471-2288-4-20
10.1136/bmj.38875.675486.55
10.2147/OPTH.S12765
10.1007/s11606-010-1387-9
10.1016/S1070-3241(16)30461-8
10.1097/MLR.0b013e31819a5acc
10.1177/1545109707301243
10.1016/S0031-9406(05)66175-5
10.1111/j.1399-0012.2006.00493.x
10.1016/0091-7435(85)90070-2
10.1097/00005650-199808000-00004
10.1001/jama.287.21.2772
10.1016/j.ypmed.2014.10.021
10.1097/00012272-198404000-00008
10.1177/1094428106296638
10.1007/s11904-009-0037-5
10.1177/0272989X05282643
10.1111/j.1399-0012.2010.01358.x
10.1177/016327870102400302
10.1177/107554708901000301
10.3310/hta3120
10.1089/apc.2005.19.745
10.1016/j.ophtha.2009.05.026
10.1093/ajhp/60.7.657
10.1191/0962280205sm415oa
10.1080/08964289.2011.651174
10.1023/B:JOCS.0000045347.69924.77
10.1345/aph.1M572
10.1300/J115v22n04_01
10.1016/j.rmed.2011.03.019
10.1331/JAPhA.2012.11083
10.1089/apc.2010.0367
10.1016/j.drugalcdep.2010.12.016
10.1016/j.amjmed.2006.08.033
10.1016/S0140-6736(00)02786-0
10.1345/aph.1L707
10.1007/s12160-011-9319-4
10.2165/00002512-199202020-00004
10.1111/j.1440-172X.2004.00476.x
10.1097/MLR.0b013e3181808c17
10.1097/JCN.0b013e3181d5f9c5
10.1007/s11883-008-0004-4
10.1080/09540120050123792
10.1037/1082-989X.7.1.105
10.1177/0193945912439251
10.1111/j.2042-7174.2011.00161.x
10.1016/j.jana.2011.04.003
10.1001/jama.282.11.1054
10.1016/j.drugalcdep.2006.09.019
10.1016/0376-8716(94)01080-5
10.1503/cmaj.090533
10.1345/aph.1D268
10.2105/AJPH.2010.194381
10.1016/j.jana.2005.07.001
10.1093/ajhp/60.11.1123
10.1001/archophthalmol.2012.1607
10.1016/S0005-7967(00)00091-7
ContentType Journal Article
Copyright 2016 Elsevier Inc.
Copyright © 2016 Elsevier Inc. All rights reserved.
Copyright_xml – notice: 2016 Elsevier Inc.
– notice: Copyright © 2016 Elsevier Inc. All rights reserved.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOI 10.1016/j.sapharm.2015.06.001
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList
MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Pharmacy, Therapeutics, & Pharmacology
EISSN 1934-8150
EndPage 246
ExternalDocumentID PMC4679728
26164400
10_1016_j_sapharm_2015_06_001
S1551741115001187
Genre Meta-Analysis
Systematic Review
Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: NINR NIH HHS
  grantid: R01NR011990
– fundername: NINR NIH HHS
  grantid: K01 NR014409
– fundername: NINR NIH HHS
  grantid: R01 NR011990
GroupedDBID ---
--K
--M
.~1
0R~
123
1B1
1CY
1~.
1~5
4.4
457
4G.
53G
5VS
7-5
71M
8P~
AACTN
AAEDT
AAEDW
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AATCM
AAWTL
AAXUO
ABIVO
ABLVK
ABMAC
ABMZM
ABXDB
ABYKQ
ABZDS
ACDAQ
ACGFS
ACHQT
ACRLP
ADBBV
ADEZE
ADMUD
AEBSH
AEKER
AFKWA
AFTJW
AFXIZ
AGHFR
AGUBO
AGYEJ
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
AJRQY
ALCLG
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ANZVX
AXJTR
BKOJK
BLXMC
BNPGV
C45
CS3
DU5
EBS
EFJIC
EFLBG
EJD
EO9
EP2
EP3
F5P
FDB
FEDTE
FIRID
FNPLU
FYGXN
G-Q
GBLVA
HVGLF
HZ~
IHE
J1W
KOM
LCYCR
M41
MO0
N9A
O-L
O9-
OAUVE
OGGZJ
OVD
OZT
P-8
P-9
P2P
PC.
Q38
RIG
ROL
RPZ
SDF
SDG
SEL
SES
SPCBC
SSH
SSP
SSZ
T5K
TEORI
~G-
AATTM
AAXKI
AAYWO
AAYXX
ABWVN
ACIEU
ACRPL
ACVFH
ADCNI
ADNMO
AEIPS
AEUPX
AFJKZ
AFPUW
AGCQF
AGRNS
AIGII
AIIUN
AKBMS
AKRWK
AKYEP
ANKPU
APXCP
CITATION
CGR
CUY
CVF
ECM
EFKBS
EIF
NPM
7X8
5PM
ID FETCH-LOGICAL-c537t-bc3bbc3f4d0a793a9bb4ffa13924a3cff76bc09cc4ac8fd077882e0e5b84c7fc3
IEDL.DBID .~1
ISSN 1551-7411
1934-8150
IngestDate Thu Aug 21 18:43:10 EDT 2025
Fri Jul 11 12:25:11 EDT 2025
Mon Jul 21 05:32:07 EDT 2025
Tue Jul 01 03:20:16 EDT 2025
Thu Apr 24 23:10:42 EDT 2025
Fri Feb 23 02:26:57 EST 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords Medication adherence
Intervention
Systematic review
Meta-analysis
Language English
License Copyright © 2016 Elsevier Inc. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c537t-bc3bbc3f4d0a793a9bb4ffa13924a3cff76bc09cc4ac8fd077882e0e5b84c7fc3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ObjectType-Undefined-4
ORCID 0000-0003-2754-4019
OpenAccessLink http://doi.org/10.1016/j.sapharm.2015.06.001
PMID 26164400
PQID 1762962626
PQPubID 23479
PageCount 29
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_4679728
proquest_miscellaneous_1762962626
pubmed_primary_26164400
crossref_citationtrail_10_1016_j_sapharm_2015_06_001
crossref_primary_10_1016_j_sapharm_2015_06_001
elsevier_sciencedirect_doi_10_1016_j_sapharm_2015_06_001
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2016-03-01
PublicationDateYYYYMMDD 2016-03-01
PublicationDate_xml – month: 03
  year: 2016
  text: 2016-03-01
  day: 01
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Research in social and administrative pharmacy
PublicationTitleAlternate Res Social Adm Pharm
PublicationYear 2016
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References DiMatteo, Giordani, Lepper, Croghan (bib1) 2002; 40
Conn, Enriquez, Ruppar, Chan (bib135) 2014; 69
Phillips (bib128) 2004; 4
Nietert, Tilley, Zhao (bib39) 2009; 47
Zolnierek, Dimatteo (bib68) 2009; 47
Wilson (bib116) 2009
Starner (bib7) 2006
Arbuthnott, Sharpe (bib67) 2009; 77
Conn, Valentine, Cooper, Rantz (bib90) 2003; 52
Ruppar (bib46) 2010; 25
de Vet, de Bie, van der Heijden, Verhagen, Sijpkes, Kipschild (bib131) 1997; 1997
Safren, Hendriksen, Mayer, Mimiaga, Pickard, Otto (bib49) 2004; 11
Manias, Williams (bib78) 2010; 44
(bib8) 2003
Bangalore, Kamalakkannan, Parkar, Messerli (bib71) 2007; 120
Borenstein, Hedges, Higgins, Rothstein (bib82) 2009
Mahid, Qadan, Hornung, Galandiuk (bib130) 2008; 95
Peeters, Van Tongelen, Boussery, Mehuys, Remon, Willems (bib136) 2011; 28
Simpson, Eurich, Majumdar (bib3) 2006; 333
Williamson, Gamble, Altman, Hutton (bib129) 2005; 14
Harper (bib21) 1984; 6
Jones (bib62) 2014; 23
Simoni, Amico, Smith, Nelson (bib74) 2010; 7
Kalichman, Cherry, Cain (bib24) 2005; 16
Turner (bib54) 1981
Matt, Cook (bib95) 1994
Hedges, Vevea (bib123) 1998; 3
Budde (bib12) 2009
Molassiotis, Lopez-Nahas, Chung, Lam (bib36) 2003; 15
Fergusson, Laupacis, Salmi, McAlister, Huet (bib101) 2000; 16
Vervloet, van Dijk, Santen-Reestman (bib56) 2012; 81
Shadish, Haddock (bib126) 2009
Wall, Sorensen, Batki, Delucchi, London, Chesney (bib58) 1995; 37
Kisamore, Brannick (bib125) 2008; 11
McPherson-Baker, Malow, Penedo, Jones, Schneiderman, Klimas (bib32) 2000; 12
Peterson, Takiya, Finley (bib65) 2003; 60
Cook, Schmiege, McClean, Aagaard, Kahook (bib141) 2012; 34
Sorensen, Haug, Delucchi (bib51) 2007; 88
Cooper, Hedges, Valentine (bib80) 2009
Leung, Busch, Nottage (bib28) 2012; 38
Bosworth (bib4) 2006
Murphy, Lu, Martin, Hoffman, Marelich (bib37) 2002; 13
Levensky (bib29) 2006
Safren, Otto, Worth (bib50) 2001; 39
Griffiths, Johnson, Piper, Langdon (bib20) 2004; 10
Lefebvre, Lusher, Dickersin, Manheimer (bib108) 2002; 359
Nochowitz, Shapiro, Nutescu, Cavallari (bib40) 2009; 43
Kalichman, Kalichman, Cherry (bib25) 2011; 25
Lee, Leung (bib27) 2003; 60
Lipsey (bib85) 2003; 587
Rothstein, Hopewell (bib93) 2009
Dickersin, Scherer, Lefebvre (bib100) 1994; 309
Zuckerman, Weiss, McNally, Layne, Mullins, Wang (bib61) 2004; 10
Glanz, Beck, Bundy (bib19) 2012; 130
Cooper (bib83) 1998
Dickersin, Scherer, Suci, Gil-Montero (bib99) 2002; 287
Sindhu, Dickson (bib106) 1997; 3
White (bib98) 2009
Lipsey (bib86) 2009
Kogos (bib26) 2004; 11
Moher, Olkin (bib88) 1995; 274
Chisholm-Burns, Spivey, Sredzinski, Butler (bib73) 2012; 52
Christiansen (bib2) 2004
Safren, Hendriksen, Desousa, Boswell, Mayer (bib48) 2003; 15
(bib6) September 28, 2010
Long, Kee, Graham, Saethang, Dames (bib30) 1998; 25
Mahtani, Heneghan, Glasziou, Perera (bib70) 2011
Pigott (bib97) 2009
Sutton (bib89) 2009
Moitra, Herbert, Forman (bib35) 2011; 23
Juni, Witschi, Bloch, Egger (bib132) 1999; 282
Dunbar-Jacob, Sereika, Houze, Luyster, Callan (bib142) 2012; 34
Alhalaiqa, Deane, Nawafleh, Clark, Gray (bib9) 2012; 26
Ali, Laurin, Lariviere, Tremblay, Cloutier (bib10) 2003; 10
Remien, Stirratt, Dolezal (bib44) 2005; 19
Cook, Bremer, Ayala, Kahook (bib14) 2010; 4
Andes, Lu, Higgins (bib124) 2005; 25
Morris, DeShon (bib119) 2002; 7
Chaudhry, McDermott (bib5) 2008; 10
Rosen, Dieckhaus, McMahon (bib45) 2007; 21
Cohen (bib118) 1988
Mitchell (bib34) 1993
Iskedjian, Einarson, MacKeigan (bib69) 2002; 24
Helmer, Savoie, Green, Kazanjian (bib105) 2001; 89
Devine (bib114) 1997
Villeneuve, Genest, Blais (bib57) 2010; 182
Lipsey, Wilson (bib84) 2001
Lohr, Carey (bib87) 1999; 25
Watakakosol (bib59) 2010
Ramirez-Garcia, Côté (bib43) 2012; 23
Lipsey, Wilson (bib117) 2001; 24
van Servellen, Nyamathi, Carpio (bib55) 2005; 19
Gamble, Stevenson, Heaney (bib18) 2011; 105
Haynes, Sackett, Gibson (bib22) 1976; 1
Russell, Conn, Ashbaugh (bib47) 2011; 25
Rivers (bib140) 1992; 2
Taylor, Byrd, Krueger (bib53) 2003; 60
Freedman (bib17) 2007
De Geest, Schafer-Keller, Denhaerynck (bib15) 2006; 20
Stewart, George, Jackson (bib52) 2007
Orwin, Vevea (bib115) 2009
Mullen, Green, Persinger (bib64) 1985; 14
Scoville, Johnson, McConnell (bib103) 2003; 22
McAuley, Pham, Tugwell, Moher (bib92) 2000; 356
Amico, Harman, Johnson (bib76) 2006; 41
Stern, Simes (bib94) 1997; 315
Reed, Baxter (bib102) 2009
Jadad, Moher, Klassen (bib91) 1998; 152
Desborough, Sach, Bhattacharya, Holland, Wright (bib16) 2012; 20
Kravitz, Melnikow (bib63) 2004; 42
Conn, Rantz (bib127) 2003; 26
Conn, Hafdahl, Mehr, LeMaster, Brown, Nielsen (bib121) 2007; 50
Roter, Hall, Merisca, Nordstrom, Cretin, Svarstad (bib66) 1998; 36
Smith, Smith, Stullenbarger (bib111) 1991; 10
Hedges, Olkin (bib120) 1985
Okeke, Quigley, Jampel (bib41) 2009; 116
Langham, Thompson, Rowen (bib110) 1999; 34
Conn, Valentine, Cooper (bib139) 2002; 24
Bailey, Cates, Kruske, Morris, Brown, Chang (bib77) 2009
Hek, Langton, Blunden (bib109) 2000; 7
Dickersin, Olson, Rennie (bib104) 2002; 287
Ingersoll, Farrell-Carnahan, Cohen-Filipic (bib23) 2011; 116
Conn, Hafdahl, Cooper, Ruppar, Mehr, Russell (bib79) 2009; 49
Easterbrook (bib107) 1992; 11
Conn, Hafdahl, Mehr (bib138) 2011; 101
Austin (bib11) 1986
Takiya, Peterson, Finley (bib75) 2004; 38
Cutrona, Choudhry, Stedman (bib72) 2010; 25
Valentine (bib134) 2009
Migneault, Dedier, Wright (bib33) 2012; 43
Cooper, Ribble (bib112) 1989; 10
Murphy, Marelich, Rappaport, Hoffman, Farthing (bib38) 2007; 6
Oser (bib42) 2008
Conn, Hafdahl, Brown, Brown (bib137) 2008; 70
Raudenbush (bib122) 2009
Burrelle (bib13) 1986; 1
Nony, Cucherat, Haugh, Boissel (bib96) 1995; 50
Wu, Leung, Chang (bib60) 2006; 333
Matteson (bib31) 2011
Wood (bib113) 2008; 11
Moher, Cook, Jadad (bib133) 1999; 3
Liberati, Altman, Tetzlaff (bib81) 2009; 62
Austin (10.1016/j.sapharm.2015.06.001_bib11) 1986
Nochowitz (10.1016/j.sapharm.2015.06.001_bib40) 2009; 43
Bosworth (10.1016/j.sapharm.2015.06.001_bib4) 2006
Conn (10.1016/j.sapharm.2015.06.001_bib137) 2008; 70
Bailey (10.1016/j.sapharm.2015.06.001_bib77) 2009
McAuley (10.1016/j.sapharm.2015.06.001_bib92) 2000; 356
Starner (10.1016/j.sapharm.2015.06.001_bib7) 2006
Taylor (10.1016/j.sapharm.2015.06.001_bib53) 2003; 60
Shadish (10.1016/j.sapharm.2015.06.001_bib126) 2009
Cutrona (10.1016/j.sapharm.2015.06.001_bib72) 2010; 25
Christiansen (10.1016/j.sapharm.2015.06.001_bib2) 2004
Pigott (10.1016/j.sapharm.2015.06.001_bib97) 2009
Chaudhry (10.1016/j.sapharm.2015.06.001_bib5) 2008; 10
Hedges (10.1016/j.sapharm.2015.06.001_bib123) 1998; 3
Borenstein (10.1016/j.sapharm.2015.06.001_bib82) 2009
Reed (10.1016/j.sapharm.2015.06.001_bib102) 2009
Murphy (10.1016/j.sapharm.2015.06.001_bib37) 2002; 13
Griffiths (10.1016/j.sapharm.2015.06.001_bib20) 2004; 10
Cohen (10.1016/j.sapharm.2015.06.001_bib118) 1988
Hedges (10.1016/j.sapharm.2015.06.001_bib120) 1985
(10.1016/j.sapharm.2015.06.001_bib6) 2010
Bangalore (10.1016/j.sapharm.2015.06.001_bib71) 2007; 120
Villeneuve (10.1016/j.sapharm.2015.06.001_bib57) 2010; 182
De Geest (10.1016/j.sapharm.2015.06.001_bib15) 2006; 20
Dickersin (10.1016/j.sapharm.2015.06.001_bib99) 2002; 287
Matt (10.1016/j.sapharm.2015.06.001_bib95) 1994
Stewart (10.1016/j.sapharm.2015.06.001_bib52) 2007
Ruppar (10.1016/j.sapharm.2015.06.001_bib46) 2010; 25
de Vet (10.1016/j.sapharm.2015.06.001_bib131) 1997; 1997
(10.1016/j.sapharm.2015.06.001_bib8) 2003
Sorensen (10.1016/j.sapharm.2015.06.001_bib51) 2007; 88
Lipsey (10.1016/j.sapharm.2015.06.001_bib117) 2001; 24
Lipsey (10.1016/j.sapharm.2015.06.001_bib84) 2001
Mullen (10.1016/j.sapharm.2015.06.001_bib64) 1985; 14
Lohr (10.1016/j.sapharm.2015.06.001_bib87) 1999; 25
Ingersoll (10.1016/j.sapharm.2015.06.001_bib23) 2011; 116
Nony (10.1016/j.sapharm.2015.06.001_bib96) 1995; 50
Remien (10.1016/j.sapharm.2015.06.001_bib44) 2005; 19
Moitra (10.1016/j.sapharm.2015.06.001_bib35) 2011; 23
Raudenbush (10.1016/j.sapharm.2015.06.001_bib122) 2009
Ramirez-Garcia (10.1016/j.sapharm.2015.06.001_bib43) 2012; 23
Rothstein (10.1016/j.sapharm.2015.06.001_bib93) 2009
Easterbrook (10.1016/j.sapharm.2015.06.001_bib107) 1992; 11
Amico (10.1016/j.sapharm.2015.06.001_bib76) 2006; 41
Okeke (10.1016/j.sapharm.2015.06.001_bib41) 2009; 116
Leung (10.1016/j.sapharm.2015.06.001_bib28) 2012; 38
Wall (10.1016/j.sapharm.2015.06.001_bib58) 1995; 37
Conn (10.1016/j.sapharm.2015.06.001_bib79) 2009; 49
Hek (10.1016/j.sapharm.2015.06.001_bib109) 2000; 7
Devine (10.1016/j.sapharm.2015.06.001_bib114) 1997
Haynes (10.1016/j.sapharm.2015.06.001_bib22) 1976; 1
Conn (10.1016/j.sapharm.2015.06.001_bib90) 2003; 52
Fergusson (10.1016/j.sapharm.2015.06.001_bib101) 2000; 16
Moher (10.1016/j.sapharm.2015.06.001_bib133) 1999; 3
Gamble (10.1016/j.sapharm.2015.06.001_bib18) 2011; 105
Conn (10.1016/j.sapharm.2015.06.001_bib135) 2014; 69
Vervloet (10.1016/j.sapharm.2015.06.001_bib56) 2012; 81
Langham (10.1016/j.sapharm.2015.06.001_bib110) 1999; 34
Burrelle (10.1016/j.sapharm.2015.06.001_bib13) 1986; 1
Kalichman (10.1016/j.sapharm.2015.06.001_bib25) 2011; 25
Lee (10.1016/j.sapharm.2015.06.001_bib27) 2003; 60
Kisamore (10.1016/j.sapharm.2015.06.001_bib125) 2008; 11
Lipsey (10.1016/j.sapharm.2015.06.001_bib85) 2003; 587
Migneault (10.1016/j.sapharm.2015.06.001_bib33) 2012; 43
Helmer (10.1016/j.sapharm.2015.06.001_bib105) 2001; 89
Mahtani (10.1016/j.sapharm.2015.06.001_bib70) 2011
Oser (10.1016/j.sapharm.2015.06.001_bib42) 2008
Moher (10.1016/j.sapharm.2015.06.001_bib88) 1995; 274
Peterson (10.1016/j.sapharm.2015.06.001_bib65) 2003; 60
Dunbar-Jacob (10.1016/j.sapharm.2015.06.001_bib142) 2012; 34
Kalichman (10.1016/j.sapharm.2015.06.001_bib24) 2005; 16
Roter (10.1016/j.sapharm.2015.06.001_bib66) 1998; 36
Phillips (10.1016/j.sapharm.2015.06.001_bib128) 2004; 4
Simpson (10.1016/j.sapharm.2015.06.001_bib3) 2006; 333
Harper (10.1016/j.sapharm.2015.06.001_bib21) 1984; 6
Chisholm-Burns (10.1016/j.sapharm.2015.06.001_bib73) 2012; 52
Nietert (10.1016/j.sapharm.2015.06.001_bib39) 2009; 47
Safren (10.1016/j.sapharm.2015.06.001_bib48) 2003; 15
Zolnierek (10.1016/j.sapharm.2015.06.001_bib68) 2009; 47
Rosen (10.1016/j.sapharm.2015.06.001_bib45) 2007; 21
Conn (10.1016/j.sapharm.2015.06.001_bib139) 2002; 24
Russell (10.1016/j.sapharm.2015.06.001_bib47) 2011; 25
Conn (10.1016/j.sapharm.2015.06.001_bib121) 2007; 50
Cooper (10.1016/j.sapharm.2015.06.001_bib112) 1989; 10
Kravitz (10.1016/j.sapharm.2015.06.001_bib63) 2004; 42
Lefebvre (10.1016/j.sapharm.2015.06.001_bib108) 2002; 359
Scoville (10.1016/j.sapharm.2015.06.001_bib103) 2003; 22
Valentine (10.1016/j.sapharm.2015.06.001_bib134) 2009
Alhalaiqa (10.1016/j.sapharm.2015.06.001_bib9) 2012; 26
Freedman (10.1016/j.sapharm.2015.06.001_bib17) 2007
Williamson (10.1016/j.sapharm.2015.06.001_bib129) 2005; 14
Smith (10.1016/j.sapharm.2015.06.001_bib111) 1991; 10
Conn (10.1016/j.sapharm.2015.06.001_bib127) 2003; 26
Watakakosol (10.1016/j.sapharm.2015.06.001_bib59) 2010
Zuckerman (10.1016/j.sapharm.2015.06.001_bib61) 2004; 10
Stern (10.1016/j.sapharm.2015.06.001_bib94) 1997; 315
Safren (10.1016/j.sapharm.2015.06.001_bib50) 2001; 39
Murphy (10.1016/j.sapharm.2015.06.001_bib38) 2007; 6
Morris (10.1016/j.sapharm.2015.06.001_bib119) 2002; 7
Juni (10.1016/j.sapharm.2015.06.001_bib132) 1999; 282
Cook (10.1016/j.sapharm.2015.06.001_bib141) 2012; 34
DiMatteo (10.1016/j.sapharm.2015.06.001_bib1) 2002; 40
Arbuthnott (10.1016/j.sapharm.2015.06.001_bib67) 2009; 77
Matteson (10.1016/j.sapharm.2015.06.001_bib31) 2011
Wilson (10.1016/j.sapharm.2015.06.001_bib116) 2009
van Servellen (10.1016/j.sapharm.2015.06.001_bib55) 2005; 19
Turner (10.1016/j.sapharm.2015.06.001_bib54) 1981
Lipsey (10.1016/j.sapharm.2015.06.001_bib86) 2009
Simoni (10.1016/j.sapharm.2015.06.001_bib74) 2010; 7
Cooper (10.1016/j.sapharm.2015.06.001_bib80) 2009
Ali (10.1016/j.sapharm.2015.06.001_bib10) 2003; 10
McPherson-Baker (10.1016/j.sapharm.2015.06.001_bib32) 2000; 12
Mitchell (10.1016/j.sapharm.2015.06.001_bib34) 1993
Orwin (10.1016/j.sapharm.2015.06.001_bib115) 2009
White (10.1016/j.sapharm.2015.06.001_bib98) 2009
Peeters (10.1016/j.sapharm.2015.06.001_bib136) 2011; 28
Cook (10.1016/j.sapharm.2015.06.001_bib14) 2010; 4
Jones (10.1016/j.sapharm.2015.06.001_bib62) 2014; 23
Sindhu (10.1016/j.sapharm.2015.06.001_bib106) 1997; 3
Budde (10.1016/j.sapharm.2015.06.001_bib12) 2009
Molassiotis (10.1016/j.sapharm.2015.06.001_bib36) 2003; 15
Cooper (10.1016/j.sapharm.2015.06.001_bib83) 1998
Long (10.1016/j.sapharm.2015.06.001_bib30) 1998; 25
Liberati (10.1016/j.sapharm.2015.06.001_bib81) 2009; 62
Wood (10.1016/j.sapharm.2015.06.001_bib113) 2008; 11
Desborough (10.1016/j.sapharm.2015.06.001_bib16) 2012; 20
Levensky (10.1016/j.sapharm.2015.06.001_bib29) 2006
Safren (10.1016/j.sapharm.2015.06.001_bib49) 2004; 11
Mahid (10.1016/j.sapharm.2015.06.001_bib130) 2008; 95
Takiya (10.1016/j.sapharm.2015.06.001_bib75) 2004; 38
Manias (10.1016/j.sapharm.2015.06.001_bib78) 2010; 44
Jadad (10.1016/j.sapharm.2015.06.001_bib91) 1998; 152
Glanz (10.1016/j.sapharm.2015.06.001_bib19) 2012; 130
Kogos (10.1016/j.sapharm.2015.06.001_bib26) 2004; 11
Conn (10.1016/j.sapharm.2015.06.001_bib138) 2011; 101
Iskedjian (10.1016/j.sapharm.2015.06.001_bib69) 2002; 24
Andes (10.1016/j.sapharm.2015.06.001_bib124) 2005; 25
Wu (10.1016/j.sapharm.2015.06.001_bib60) 2006; 333
Dickersin (10.1016/j.sapharm.2015.06.001_bib100) 1994; 309
Sutton (10.1016/j.sapharm.2015.06.001_bib89) 2009
Dickersin (10.1016/j.sapharm.2015.06.001_bib104) 2002; 287
Rivers (10.1016/j.sapharm.2015.06.001_bib140) 1992; 2
References_xml – year: September 28, 2010
  ident: bib6
  article-title: Just What the Doctor Ordered: An EU Response to Medication Nonadherence
– volume: 34
  start-page: 25
  year: 1999
  end-page: 34
  ident: bib110
  article-title: Identification of randomized controlled trials from the emergency medicine literature: comparison of hand searching versus MEDLINE searching
  publication-title: Ann Emerg Med
– volume: 11
  start-page: 79
  year: 2008
  end-page: 95
  ident: bib113
  article-title: Methodology for dealing with duplicate study effects in a meta-analysis
  publication-title: Organ Res Methods
– volume: 70
  start-page: 157
  year: 2008
  end-page: 172
  ident: bib137
  article-title: Meta-analysis of patient education interventions to increase physical activity among chronically ill adults
  publication-title: Patient Educ Couns
– volume: 3
  year: 1999
  ident: bib133
  article-title: Assessing the quality of reports of randomised trials: implications for the conduct of meta-analyses
  publication-title: Health Technol Assess
– volume: 52
  start-page: 256
  year: 2003
  end-page: 261
  ident: bib90
  article-title: Grey literature in meta-analyses
  publication-title: Nurs Res
– year: 1998
  ident: bib83
  article-title: Synthesizing Research
– volume: 26
  start-page: 322
  year: 2003
  end-page: 333
  ident: bib127
  article-title: Research methods: managing primary study quality in meta-analyses
  publication-title: Res Nurs Health
– volume: 309
  start-page: 1286
  year: 1994
  end-page: 1291
  ident: bib100
  article-title: Identifying relevant studies for systematic reviews
  publication-title: BMJ
– start-page: 295
  year: 2009
  end-page: 315
  ident: bib122
  article-title: Random effects models
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 1
  start-page: 23
  year: 1986
  end-page: 51
  ident: bib13
  article-title: Evaluation of an interdisciplinary compliance service for elderly hypertensives
  publication-title: J Geriatr Drug Ther
– volume: 15
  start-page: 787
  year: 2003
  end-page: 793
  ident: bib48
  article-title: Use of an on-line pager system to increase adherence to antiretroviral medications
  publication-title: AIDS Care
– volume: 14
  start-page: 515
  year: 2005
  end-page: 524
  ident: bib129
  article-title: Outcome selection bias in meta-analysis
  publication-title: Stat Methods Med Res
– start-page: 503
  year: 1994
  end-page: 519
  ident: bib95
  article-title: Threats to the validity of research synthesis
  publication-title: The Handbook of Research Synthesis
– volume: 16
  start-page: 1109
  year: 2000
  end-page: 1119
  ident: bib101
  article-title: What should be included in meta-analyses? An exploration of methodological issues using the ISPOT meta-analyses
  publication-title: Int J Technol Assess Health Care
– volume: 333
  start-page: 522
  year: 2006
  end-page: 525
  ident: bib60
  article-title: Effectiveness of telephone counseling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial
  publication-title: Br Med J
– volume: 15
  start-page: 125
  year: 2003
  end-page: 135
  ident: bib36
  article-title: A pilot study of the effects of a behavioural intervention on treatment adherence in HIV-infected patients
  publication-title: AIDS Care
– year: 1993
  ident: bib34
  article-title: Effects of a Self-efficacy Intervention on Adherence to Antihypertensive Regimens
– year: 2006
  ident: bib29
  article-title: Further Development and Evaluation of an Individualized Intervention for Increasing Adherence to HIV Medications
– volume: 25
  start-page: 864
  year: 2011
  end-page: 870
  ident: bib47
  article-title: Taking immunosuppressive medications effectively (TIMELink): a pilot randomized controlled trial in adult kidney transplant recipients
  publication-title: Clin Transpl
– volume: 41
  start-page: 285
  year: 2006
  end-page: 297
  ident: bib76
  article-title: Efficacy of antiretroviral therapy adherence interventions: a research synthesis of trials, 1996 to 2004
  publication-title: J Acquir Immune Defic Syndr
– volume: 12
  start-page: 399
  year: 2000
  end-page: 404
  ident: bib32
  article-title: Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive men
  publication-title: AIDS Care
– volume: 7
  start-page: 44
  year: 2010
  end-page: 51
  ident: bib74
  article-title: Antiretroviral adherence interventions: translating research findings to the real world clinic
  publication-title: Curr HIV/AIDS Rep
– volume: 182
  start-page: 447
  year: 2010
  end-page: 455
  ident: bib57
  article-title: A cluster randomized controlled trial to evaluate an ambulatory primary care management program for patients with dyslipidemia: the TEAM study
  publication-title: Can Med Assoc J
– volume: 10
  start-page: 101
  year: 2003
  end-page: 106
  ident: bib10
  article-title: The effect of pharmacist intervention and patient education on lipid-lowering medication compliance and plasma cholesterol levels
  publication-title: Can J Clin Pharmacol
– volume: 11
  start-page: 415
  year: 2004
  end-page: 424
  ident: bib49
  article-title: Cognitive-behavioral therapy for HIV medication adherence and depression
  publication-title: Cogn Behav Pract
– volume: 25
  start-page: 646
  year: 2005
  end-page: 654
  ident: bib124
  article-title: The interpretation of random-effects meta-analysis in decision models
  publication-title: Med Decis Making
– year: 1981
  ident: bib54
  article-title: Effects of a Behavioral Self-control Package on Drug Prescription Compliance Behavior of Chronic Arthritic Patients
– volume: 77
  start-page: 60
  year: 2009
  end-page: 67
  ident: bib67
  article-title: The effect of physician-patient collaboration on patient adherence in non-psychiatric medicine
  publication-title: Patient Educ Couns
– start-page: 399
  year: 2009
  end-page: 416
  ident: bib97
  article-title: Handling missing data
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– year: 2006
  ident: bib7
  article-title: The Price of Noncompliance
– volume: 116
  start-page: 2286
  year: 2009
  end-page: 2293
  ident: bib41
  article-title: Interventions improve poor adherence with once daily glaucoma medications in electronically monitored patients
  publication-title: Ophthalmology
– volume: 47
  start-page: 826
  year: 2009
  end-page: 834
  ident: bib68
  article-title: Physician communication and patient adherence to treatment: a meta-analysis
  publication-title: Med Care
– volume: 40
  start-page: 794
  year: 2002
  end-page: 811
  ident: bib1
  article-title: Patient adherence and medical treatment outcomes: a meta-analysis
  publication-title: Med Care
– volume: 44
  start-page: 964
  year: 2010
  end-page: 982
  ident: bib78
  article-title: Medication adherence in people of culturally and linguistically diverse backgrounds: a meta-analysis
  publication-title: Ann Pharmacother
– volume: 21
  start-page: 30
  year: 2007
  end-page: 40
  ident: bib45
  article-title: Improved adherence with contingency management
  publication-title: AIDS Patient Care STDS
– volume: 4
  start-page: 1091
  year: 2010
  end-page: 1101
  ident: bib14
  article-title: Feasibility of motivational interviewing delivered by a glaucoma educator to improve medication adherence
  publication-title: Clin Ophthalmol
– volume: 11
  start-page: 363
  year: 1992
  end-page: 423
  ident: bib107
  article-title: Directory of registries of clinical trials
  publication-title: Stat Med
– volume: 7
  start-page: 40
  year: 2000
  end-page: 57
  ident: bib109
  article-title: Systematically searching and reviewing literature
  publication-title: Nurse Res
– volume: 10
  start-page: 179
  year: 1989
  end-page: 201
  ident: bib112
  article-title: Influences on the outcomes of literature searches for integrative research reviews
  publication-title: Knowledge
– start-page: 147
  year: 2009
  end-page: 158
  ident: bib86
  article-title: Identifying interesting variables and analysis opportunities
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 130
  start-page: 1252
  year: 2012
  end-page: 1258
  ident: bib19
  article-title: Impact of a health communication intervention to improve glaucoma treatment adherence: results of the interactive study to increase glaucoma adherence to treatment trial
  publication-title: Arch Ophthalmol
– volume: 16
  start-page: 3
  year: 2005
  end-page: 15
  ident: bib24
  article-title: Nurse-delivered antiretroviral treatment adherence intervention for people with low literacy skills and living with HIV/AIDS
  publication-title: J Assoc Nurses AIDS Care
– volume: 50
  start-page: 913
  year: 2007
  end-page: 921
  ident: bib121
  article-title: Metabolic effects of interventions to increase exercise in adults with type 2 diabetes
  publication-title: Diabetologia
– volume: 23
  start-page: 38
  year: 2014
  end-page: 41
  ident: bib62
  article-title: Medication adherence study looks at types of interventions
  publication-title: Manag Care
– volume: 39
  start-page: 1151
  year: 2001
  end-page: 1162
  ident: bib50
  article-title: Two strategies to increase adherence to HIV antiretroviral medication: life-Steps and medication monitoring
  publication-title: Behav Res Ther
– volume: 88
  start-page: 54
  year: 2007
  end-page: 63
  ident: bib51
  article-title: Voucher reinforcement improves medication adherence in HIV-positive methadone patients: a randomized trial
  publication-title: Drug Alcohol Depend
– volume: 52
  start-page: 816
  year: 2012
  end-page: 822
  ident: bib73
  article-title: Intervention toolbox to promote immunosuppressant therapy adherence in adult renal transplant recipients
  publication-title: J Am Pharm Assoc (2003)
– volume: 23
  start-page: 220
  year: 2012
  end-page: 232
  ident: bib43
  article-title: An individualized intervention to foster optimal antiretroviral treatment-taking behavior among persons living with HIV: a pilot randomized controlled trial
  publication-title: J Assoc Nurses AIDS Care
– volume: 60
  start-page: 1123
  year: 2003
  end-page: 1129
  ident: bib53
  article-title: Improving primary care in rural Alabama with a pharmacy initiative
  publication-title: Am J Health Syst Pharm
– start-page: 130
  year: 1997
  end-page: 146
  ident: bib114
  article-title: Issues and challenges in coding interventions for meta-analysis of prevention research
  publication-title: Meta-analysis of Drug Abuse Prevention Programs
– volume: 81
  start-page: 594
  year: 2012
  end-page: 604
  ident: bib56
  article-title: SMS reminders improve adherence to oral medication in type 2 diabetes patients who are real time electronically monitored
  publication-title: Int J Med Inf
– volume: 1997
  start-page: 284
  year: 1997
  end-page: 289
  ident: bib131
  article-title: Systematic review on the basis of methodological criteria
  publication-title: Physiotherapy
– volume: 19
  start-page: 745
  year: 2005
  end-page: 759
  ident: bib55
  article-title: Effects of a treatment adherence enhancement program on health literacy, patient-provider relationships, and adherence to HAART among low-income HIV-positive Spanish-speaking Latinos
  publication-title: AIDS Patient Care STDS
– volume: 43
  start-page: 1165
  year: 2009
  end-page: 1172
  ident: bib40
  article-title: Effect of a warfarin adherence aid on anticoagulation control in an inner-city anticoagulation clinic population
  publication-title: Ann Pharmacother
– volume: 274
  start-page: 1962
  year: 1995
  end-page: 1964
  ident: bib88
  article-title: Meta-analysis of randomized controlled trials: a concern for standards
  publication-title: J Am Med Assoc
– volume: 287
  start-page: 2772
  year: 2002
  end-page: 2774
  ident: bib99
  article-title: Problems with indexing and citation of articles with group authorship
  publication-title: J Am Med Assoc
– volume: 3
  start-page: 486
  year: 1998
  end-page: 504
  ident: bib123
  article-title: Fixed- and random-effects models in meta-analysis
  publication-title: Psychol Methods
– year: 1985
  ident: bib120
  article-title: Statistical Methods for Meta-analysis
– volume: 10
  start-page: 166
  year: 2004
  end-page: 176
  ident: bib20
  article-title: A nursing intervention for the quality use of medicines by elderly community clients
  publication-title: Int J Nurs Pract
– volume: 38
  start-page: 1617
  year: 2004
  end-page: 1624
  ident: bib75
  article-title: Meta-analysis of interventions for medication adherence to antihypertensives
  publication-title: Ann Pharmacother
– volume: 10
  start-page: 47
  year: 1991
  end-page: 72
  ident: bib111
  article-title: Decision points in the integrative research review process: a flow-chart approach
  publication-title: Med Ref Serv Q
– volume: 89
  start-page: 346
  year: 2001
  end-page: 352
  ident: bib105
  article-title: Evidence-based practice: extending the search to find material for the systematic review
  publication-title: Bull Med Libr Assoc
– volume: 34
  start-page: 598
  year: 2012
  end-page: 620
  ident: bib141
  article-title: Practical and analytic issues in the electronic assessment of adherence
  publication-title: West J Nurs Res
– volume: 60
  start-page: 2593
  year: 2003
  end-page: 2596
  ident: bib27
  article-title: Glycemic control and medication compliance in diabetic patients in a pharmacist-managed clinic in Hong Kong
  publication-title: Am J Health Syst Pharm
– start-page: CD006580
  year: 2009
  ident: bib77
  article-title: Culture-specific programs for children and adults from minority groups who have asthma
  publication-title: Cochrane Database Syst Rev
– start-page: 129
  year: 2009
  end-page: 146
  ident: bib134
  article-title: Judging the quality of primary research
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 10
  start-page: 493
  year: 2004
  end-page: 500
  ident: bib61
  article-title: Impact of an educational intervention for secondary prevention of myocardial infarction on Medicaid drug use and cost
  publication-title: Am J Manag Care
– volume: 20
  start-page: 41
  year: 2012
  end-page: 49
  ident: bib16
  article-title: A cost-consequences analysis of an adherence focused pharmacist-led medication review service
  publication-title: Int J Pharm Pract
– year: 2011
  ident: bib31
  article-title: A Pilot Intervention to Improve Medication Adherence in Nonadherent Inflammatory Bowel Disease Patients
– volume: 101
  start-page: 751
  year: 2011
  end-page: 758
  ident: bib138
  article-title: Interventions to increase physical activity among healthy adults: meta-analysis of outcomes
  publication-title: Am J Public Health
– start-page: 159
  year: 2009
  end-page: 176
  ident: bib116
  article-title: Systematic coding
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 11
  start-page: 275
  year: 2004
  end-page: 282
  ident: bib26
  article-title: Support groups and treatment adherence in a geriatric outpatient clinic
  publication-title: J Clin Psychol Med Settings
– year: 2001
  ident: bib84
  article-title: Practical Meta-analysis
– volume: 3
  start-page: 211
  year: 1997
  end-page: 217
  ident: bib106
  article-title: The complexity of searching the literature
  publication-title: Int J Nurs Pract
– volume: 49
  start-page: 447
  year: 2009
  end-page: 462
  ident: bib79
  article-title: Interventions to improve medication adherence among older adults: meta-analysis of adherence outcomes among randomized controlled trials
  publication-title: Gerontologist
– year: 2010
  ident: bib59
  article-title: Telephone-administered Intervention to Improve Medication Adherence in HIV-infected Rural Persons: A Pilot Randomized Clinical Trial
– volume: 11
  start-page: 35
  year: 2008
  end-page: 53
  ident: bib125
  article-title: An illustration of the consequences of meta-analysis model choice
  publication-title: Organ Res Methods
– volume: 10
  start-page: 19
  year: 2008
  end-page: 24
  ident: bib5
  article-title: Recognizing and improving patient nonadherence to statin therapy
  publication-title: Curr Atheroscler Rep
– year: 1986
  ident: bib11
  article-title: Selected Nursing Interventions for Noncompliant Hypertensive Patients
– start-page: 147
  year: 2006
  end-page: 194
  ident: bib4
  article-title: Medication treatment adherence
  publication-title: Patient Treatment Adherence: Concepts, Interventions, and Measurement
– volume: 120
  start-page: 713
  year: 2007
  end-page: 719
  ident: bib71
  article-title: Fixed-dose combinations improve medication compliance: a meta-analysis
  publication-title: Am J Med
– volume: 25
  start-page: 470
  year: 1999
  end-page: 479
  ident: bib87
  article-title: Assessing “best evidence”: issues in grading the quality of studies for systematic reviews
  publication-title: Jt Comm J Qual Improv
– volume: 24
  start-page: 236
  year: 2001
  end-page: 254
  ident: bib117
  article-title: The way in which intervention studies have “personality” and why it is important to meta-analysis
  publication-title: Eval Health Prof
– volume: 7
  start-page: 105
  year: 2002
  end-page: 125
  ident: bib119
  article-title: Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs
  publication-title: Psychol Methods
– start-page: 257
  year: 2009
  end-page: 277
  ident: bib126
  article-title: Combining estimates of effect size
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 95
  start-page: 943
  year: 2008
  end-page: 949
  ident: bib130
  article-title: Assessment of publication bias for the surgeon scientist
  publication-title: Br J Surg
– volume: 28
  start-page: 262
  year: 2011
  end-page: 275
  ident: bib136
  article-title: Factors associated with medication adherence to oral hypoglycaemic agents in different ethnic groups suffering from type 2 diabetes: a systematic literature review and suggestions for further research
  publication-title: Diabet Med
– year: 2004
  ident: bib2
  article-title: Patient Adherence to Medical Treatment Regimens: Bridging the Gap Between Behavioral Science and Biomedicine
– volume: 287
  start-page: 2829
  year: 2002
  end-page: 2831
  ident: bib104
  article-title: Association between time interval to publication and statistical significance
  publication-title: J Am Med Assoc
– year: 2009
  ident: bib82
  article-title: Introduction to Meta-analysis
– volume: 34
  start-page: 578
  year: 2012
  end-page: 597
  ident: bib142
  article-title: Accuracy of measures of medication adherence in a cholesterol-lowering regimen
  publication-title: West J Nurs Res
– volume: 105
  start-page: 1308
  year: 2011
  end-page: 1315
  ident: bib18
  article-title: A study of a multi-level intervention to improve non-adherence in difficult to control asthma
  publication-title: Respir Med
– year: 2003
  ident: bib8
  article-title: Adherence to Long-term Therapies: Evidence for Action
– volume: 6
  start-page: 113
  year: 2007
  end-page: 124
  ident: bib38
  article-title: Results of an antiretroviral adherence intervention: STAR (Staying Healthy: Taking Antiretrovirals Regularly)
  publication-title: J Int Assoc Physicians AIDS Care
– volume: 2
  start-page: 103
  year: 1992
  end-page: 111
  ident: bib140
  article-title: Compliance aids—do they work?
  publication-title: Drugs Aging
– start-page: 51
  year: 2009
  end-page: 71
  ident: bib98
  article-title: Scientific communication and literature retrieval
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– year: 2009
  ident: bib12
  article-title: Increasing Regimen Adherence in Young Adults with Type 1 Diabetes
– volume: 13
  start-page: 57
  year: 2002
  end-page: 69
  ident: bib37
  article-title: Results of a pilot intervention trial to improve antiretroviral adherence among HIV-positive patients
  publication-title: J Assoc Nurses AIDS Care
– volume: 1
  start-page: 1265
  year: 1976
  end-page: 1268
  ident: bib22
  article-title: Improvement of medication compliance in uncontrolled hypertension
  publication-title: Lancet
– volume: 37
  start-page: 261
  year: 1995
  end-page: 269
  ident: bib58
  article-title: Adherence to zidovudine (AZT) among HIV-infected methadone patients: a pilot study of supervised therapy and dispensing compared to usual care
  publication-title: Drug Alcohol Depend
– volume: 20
  start-page: 359
  year: 2006
  end-page: 368
  ident: bib15
  article-title: Supporting medication adherence in renal transplantation (SMART): a pilot RCT to improve adherence to immunosuppressive regimens
  publication-title: Clin Transplant
– volume: 25
  start-page: 43
  year: 1998
  end-page: 49
  ident: bib30
  article-title: Medication compliance and the older hemodialysis patient
  publication-title: ANNA J
– start-page: 435
  year: 2009
  end-page: 452
  ident: bib89
  article-title: Publication bias
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 24
  start-page: 190
  year: 2002
  end-page: 200
  ident: bib139
  article-title: Interventions to increase physical activity among aging adults: a meta-analysis
  publication-title: Ann Behav Med
– volume: 26
  start-page: 117
  year: 2012
  end-page: 126
  ident: bib9
  article-title: Adherence therapy for medication non-compliant patients with hypertension: a randomised controlled trial
  publication-title: J Hum Hypertens
– year: 2007
  ident: bib17
  article-title: The Effects of Group Mental Health Intervention on Adherence to Medication for People With HIV and AIDS
– volume: 25
  start-page: 470
  year: 2010
  end-page: 479
  ident: bib46
  article-title: Randomized pilot study of a behavioral feedback intervention to improve medication adherence in older adults with hypertension
  publication-title: J Cardiovasc Nurs
– volume: 25
  start-page: 1090
  year: 2010
  end-page: 1096
  ident: bib72
  article-title: Physician effectiveness in interventions to improve cardiovascular medication adherence: a systematic review
  publication-title: J Gen Intern Med
– year: 1988
  ident: bib118
  article-title: Statistical Power Analysis for the Behavioral Sciences
– volume: 47
  start-page: 32
  year: 2009
  end-page: 40
  ident: bib39
  article-title: Two pharmacy interventions to improve refill persistence for chronic disease medications: a randomized, controlled trial
  publication-title: Med Care
– volume: 359
  start-page: 896
  year: 2002
  ident: bib108
  article-title: Literature searches
  publication-title: Lancet
– volume: 356
  start-page: 1228
  year: 2000
  end-page: 1231
  ident: bib92
  article-title: Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses?
  publication-title: Lancet
– volume: 43
  start-page: 62
  year: 2012
  end-page: 73
  ident: bib33
  article-title: A culturally adapted telecommunication system to improve physical activity, diet quality, and medication adherence among hypertensive African–Americans: a randomized controlled trial
  publication-title: Ann Behav Med
– volume: 14
  start-page: 753
  year: 1985
  end-page: 781
  ident: bib64
  article-title: Clinical trials of patient education for chronic conditions: a comparative meta-analysis of intervention types
  publication-title: Prev Med
– volume: 62
  start-page: e1
  year: 2009
  end-page: 34
  ident: bib81
  article-title: The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
  publication-title: J Clin Epidemiol
– volume: 24
  start-page: 302
  year: 2002
  end-page: 316
  ident: bib69
  article-title: Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: evidence from a meta-analysis
  publication-title: Clin Ther
– start-page: 103
  year: 2009
  end-page: 125
  ident: bib93
  article-title: Grey literature
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 315
  start-page: 640
  year: 1997
  end-page: 645
  ident: bib94
  article-title: Publication bias: evidence of delayed publication in a cohort study of clinical research projects
  publication-title: BMJ
– volume: 25
  start-page: 303
  year: 2011
  end-page: 310
  ident: bib25
  article-title: Brief behavioral self-regulation counseling for HIV treatment adherence delivered by cell phone: an initial test of concept trial
  publication-title: AIDS Patient Care STDS
– year: 2008
  ident: bib42
  article-title: Evaluation of a Bibliotherapy Intervention for Improving Patients' Adherence to Antihypertensive Medications
– volume: 587
  start-page: 69
  year: 2003
  end-page: 81
  ident: bib85
  article-title: Those confounded moderators in meta-analysis: good, bad, and ugly
  publication-title: Ann Am Acad Pol Soc Sci
– volume: 69
  start-page: 239
  year: 2014
  end-page: 247
  ident: bib135
  article-title: Cultural relevance in medication adherence interventions with underrepresented adults: systematic review and meta-analysis of outcomes
  publication-title: Prev Med
– volume: 282
  start-page: 1054
  year: 1999
  end-page: 1060
  ident: bib132
  article-title: The hazards of scoring the quality of clinical trials for meta-analysis
  publication-title: J Am Med Assoc
– year: 2009
  ident: bib80
  article-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 152
  start-page: 812
  year: 1998
  end-page: 817
  ident: bib91
  article-title: Guides for reading and interpreting systematic reviews: II. How did the authors find the studies and assess their quality?
  publication-title: Arch Pediatr Adolesc Med
– year: 2007
  ident: bib52
  article-title: Increasing Community Pharmacy Involvement in the Prevention of Cardiovascular Disease
– start-page: 73
  year: 2009
  end-page: 101
  ident: bib102
  article-title: Using reference databases
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 116
  start-page: 177
  year: 2011
  end-page: 187
  ident: bib23
  article-title: A pilot randomized clinical trial of two medication adherence and drug use interventions for HIV+ crack cocaine users
  publication-title: Drug Alcohol Depend
– volume: 42
  start-page: 197
  year: 2004
  end-page: 199
  ident: bib63
  article-title: Medical adherence research: time for a change in direction?
  publication-title: Med Care
– volume: 60
  start-page: 657
  year: 2003
  end-page: 665
  ident: bib65
  article-title: Meta-analysis of trials of interventions to improve medication adherence
  publication-title: Am J Health Syst Pharm
– volume: 50
  start-page: 339
  year: 1995
  end-page: 351
  ident: bib96
  article-title: Critical reading of the meta-analysis of clinical trials
  publication-title: Therapie
– volume: 6
  start-page: 29
  year: 1984
  end-page: 46
  ident: bib21
  article-title: Application of Orem's theoretical constructs to self-care medication behaviors in the elderly
  publication-title: ANS Adv Nurs Sci
– volume: 4
  start-page: 20
  year: 2004
  ident: bib128
  article-title: Publication bias in situ
  publication-title: BMC Med Res Methodol
– start-page: 177
  year: 2009
  end-page: 203
  ident: bib115
  article-title: Evaluating coding decisions
  publication-title: The Handbook of Research Synthesis and Meta-analysis
– volume: 23
  start-page: 1660
  year: 2011
  end-page: 1667
  ident: bib35
  article-title: Acceptance-based behavior therapy to promote HIV medication adherence
  publication-title: AIDS Care
– volume: 19
  start-page: 807
  year: 2005
  end-page: 814
  ident: bib44
  article-title: Couple-focused support to improve HIV medication adherence: a randomized controlled trial
  publication-title: AIDS
– start-page: CD005025
  year: 2011
  ident: bib70
  article-title: Reminder packaging for improving adherence to self-administered long-term medications
  publication-title: Cochrane Database Syst Rev
– volume: 333
  start-page: 15
  year: 2006
  ident: bib3
  article-title: A meta-analysis of the association between adherence to drug therapy and mortality
  publication-title: Br Med J
– volume: 38
  start-page: 19
  year: 2012
  end-page: 27
  ident: bib28
  article-title: Approach to antihypertensive adherence: a feasibility study on the use of student health coaches for uninsured hypertensive adults
  publication-title: Behav Med
– volume: 22
  start-page: 1
  year: 2003
  end-page: 11
  ident: bib103
  article-title: When A. Rose is not A. Rose: the vagaries of author searching
  publication-title: Med Ref Serv Q
– volume: 36
  start-page: 1138
  year: 1998
  end-page: 1161
  ident: bib66
  article-title: Effectiveness of interventions to improve patient compliance: a meta-analysis
  publication-title: Med Care
– volume: 15
  start-page: 787
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib48
  article-title: Use of an on-line pager system to increase adherence to antiretroviral medications
  publication-title: AIDS Care
  doi: 10.1080/09540120310001618630
– volume: 49
  start-page: 447
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib79
  article-title: Interventions to improve medication adherence among older adults: meta-analysis of adherence outcomes among randomized controlled trials
  publication-title: Gerontologist
  doi: 10.1093/geront/gnp037
– volume: 25
  start-page: 43
  year: 1998
  ident: 10.1016/j.sapharm.2015.06.001_bib30
  article-title: Medication compliance and the older hemodialysis patient
  publication-title: ANNA J
– volume: 315
  start-page: 640
  year: 1997
  ident: 10.1016/j.sapharm.2015.06.001_bib94
  article-title: Publication bias: evidence of delayed publication in a cohort study of clinical research projects
  publication-title: BMJ
  doi: 10.1136/bmj.315.7109.640
– volume: 50
  start-page: 913
  year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib121
  article-title: Metabolic effects of interventions to increase exercise in adults with type 2 diabetes
  publication-title: Diabetologia
  doi: 10.1007/s00125-007-0625-0
– volume: 11
  start-page: 35
  year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib125
  article-title: An illustration of the consequences of meta-analysis model choice
  publication-title: Organ Res Methods
  doi: 10.1177/1094428106287393
– year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib29
– start-page: 103
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib93
  article-title: Grey literature
– year: 1986
  ident: 10.1016/j.sapharm.2015.06.001_bib11
– start-page: 51
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib98
  article-title: Scientific communication and literature retrieval
– volume: 81
  start-page: 594
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib56
  article-title: SMS reminders improve adherence to oral medication in type 2 diabetes patients who are real time electronically monitored
  publication-title: Int J Med Inf
  doi: 10.1016/j.ijmedinf.2012.05.005
– volume: 333
  start-page: 522
  year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib60
  article-title: Effectiveness of telephone counseling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial
  publication-title: Br Med J
  doi: 10.1136/bmj.38905.447118.2F
– start-page: 147
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib86
  article-title: Identifying interesting variables and analysis opportunities
– year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib42
– year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib6
– volume: 77
  start-page: 60
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib67
  article-title: The effect of physician-patient collaboration on patient adherence in non-psychiatric medicine
  publication-title: Patient Educ Couns
  doi: 10.1016/j.pec.2009.03.022
– volume: 1
  start-page: 23
  year: 1986
  ident: 10.1016/j.sapharm.2015.06.001_bib13
  article-title: Evaluation of an interdisciplinary compliance service for elderly hypertensives
  publication-title: J Geriatr Drug Ther
– volume: 52
  start-page: 256
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib90
  article-title: Grey literature in meta-analyses
  publication-title: Nurs Res
  doi: 10.1097/00006199-200307000-00008
– volume: 11
  start-page: 363
  year: 1992
  ident: 10.1016/j.sapharm.2015.06.001_bib107
  article-title: Directory of registries of clinical trials
  publication-title: Stat Med
  doi: 10.1002/sim.4780110307
– volume: 50
  start-page: 339
  year: 1995
  ident: 10.1016/j.sapharm.2015.06.001_bib96
  article-title: Critical reading of the meta-analysis of clinical trials
  publication-title: Therapie
– volume: 19
  start-page: 807
  year: 2005
  ident: 10.1016/j.sapharm.2015.06.001_bib44
  article-title: Couple-focused support to improve HIV medication adherence: a randomized controlled trial
  publication-title: AIDS
  doi: 10.1097/01.aids.0000168975.44219.45
– volume: 62
  start-page: e1
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib81
  article-title: The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
  publication-title: J Clin Epidemiol
  doi: 10.1016/j.jclinepi.2009.06.006
– start-page: 130
  year: 1997
  ident: 10.1016/j.sapharm.2015.06.001_bib114
  article-title: Issues and challenges in coding interventions for meta-analysis of prevention research
– year: 1993
  ident: 10.1016/j.sapharm.2015.06.001_bib34
– volume: 40
  start-page: 794
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib1
  article-title: Patient adherence and medical treatment outcomes: a meta-analysis
  publication-title: Med Care
  doi: 10.1097/00005650-200209000-00009
– volume: 3
  start-page: 211
  year: 1997
  ident: 10.1016/j.sapharm.2015.06.001_bib106
  article-title: The complexity of searching the literature
  publication-title: Int J Nurs Pract
  doi: 10.1111/j.1440-172X.1997.tb00104.x
– start-page: 147
  year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib4
  article-title: Medication treatment adherence
– start-page: 295
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib122
  article-title: Random effects models
– volume: 587
  start-page: 69
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib85
  article-title: Those confounded moderators in meta-analysis: good, bad, and ugly
  publication-title: Ann Am Acad Pol Soc Sci
  doi: 10.1177/0002716202250791
– year: 2001
  ident: 10.1016/j.sapharm.2015.06.001_bib84
– volume: 3
  start-page: 486
  year: 1998
  ident: 10.1016/j.sapharm.2015.06.001_bib123
  article-title: Fixed- and random-effects models in meta-analysis
  publication-title: Psychol Methods
  doi: 10.1037/1082-989X.3.4.486
– volume: 24
  start-page: 302
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib69
  article-title: Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: evidence from a meta-analysis
  publication-title: Clin Ther
  doi: 10.1016/S0149-2918(02)85026-3
– year: 1988
  ident: 10.1016/j.sapharm.2015.06.001_bib118
– year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib12
– volume: 23
  start-page: 1660
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib35
  article-title: Acceptance-based behavior therapy to promote HIV medication adherence
  publication-title: AIDS Care
  doi: 10.1080/09540121.2011.579945
– volume: 21
  start-page: 30
  year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib45
  article-title: Improved adherence with contingency management
  publication-title: AIDS Patient Care STDS
  doi: 10.1089/apc.2006.0028
– year: 1981
  ident: 10.1016/j.sapharm.2015.06.001_bib54
– start-page: 503
  year: 1994
  ident: 10.1016/j.sapharm.2015.06.001_bib95
  article-title: Threats to the validity of research synthesis
– volume: 274
  start-page: 1962
  year: 1995
  ident: 10.1016/j.sapharm.2015.06.001_bib88
  article-title: Meta-analysis of randomized controlled trials: a concern for standards
  publication-title: J Am Med Assoc
  doi: 10.1001/jama.1995.03530240072044
– volume: 42
  start-page: 197
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib63
  article-title: Medical adherence research: time for a change in direction?
  publication-title: Med Care
  doi: 10.1097/01.mlr.0000115957.44388.7c
– volume: 34
  start-page: 25
  year: 1999
  ident: 10.1016/j.sapharm.2015.06.001_bib110
  article-title: Identification of randomized controlled trials from the emergency medicine literature: comparison of hand searching versus MEDLINE searching
  publication-title: Ann Emerg Med
  doi: 10.1016/S0196-0644(99)70268-4
– volume: 152
  start-page: 812
  year: 1998
  ident: 10.1016/j.sapharm.2015.06.001_bib91
  article-title: Guides for reading and interpreting systematic reviews: II. How did the authors find the studies and assess their quality?
  publication-title: Arch Pediatr Adolesc Med
  doi: 10.1001/archpedi.152.8.812
– year: 1998
  ident: 10.1016/j.sapharm.2015.06.001_bib83
– start-page: 257
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib126
  article-title: Combining estimates of effect size
– volume: 26
  start-page: 117
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib9
  article-title: Adherence therapy for medication non-compliant patients with hypertension: a randomised controlled trial
  publication-title: J Hum Hypertens
  doi: 10.1038/jhh.2010.133
– year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib80
– volume: 11
  start-page: 415
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib49
  article-title: Cognitive-behavioral therapy for HIV medication adherence and depression
  publication-title: Cogn Behav Pract
  doi: 10.1016/S1077-7229(04)80058-0
– volume: 41
  start-page: 285
  year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib76
  article-title: Efficacy of antiretroviral therapy adherence interventions: a research synthesis of trials, 1996 to 2004
  publication-title: J Acquir Immune Defic Syndr
  doi: 10.1097/01.qai.0000197870.99196.ea
– volume: 15
  start-page: 125
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib36
  article-title: A pilot study of the effects of a behavioural intervention on treatment adherence in HIV-infected patients
  publication-title: AIDS Care
  doi: 10.1080/0954012021000039833
– volume: 28
  start-page: 262
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib136
  article-title: Factors associated with medication adherence to oral hypoglycaemic agents in different ethnic groups suffering from type 2 diabetes: a systematic literature review and suggestions for further research
  publication-title: Diabet Med
  doi: 10.1111/j.1464-5491.2010.03133.x
– volume: 309
  start-page: 1286
  year: 1994
  ident: 10.1016/j.sapharm.2015.06.001_bib100
  article-title: Identifying relevant studies for systematic reviews
  publication-title: BMJ
  doi: 10.1136/bmj.309.6964.1286
– volume: 10
  start-page: 47
  year: 1991
  ident: 10.1016/j.sapharm.2015.06.001_bib111
  article-title: Decision points in the integrative research review process: a flow-chart approach
  publication-title: Med Ref Serv Q
  doi: 10.1300/J115v10n02_04
– volume: 24
  start-page: 190
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib139
  article-title: Interventions to increase physical activity among aging adults: a meta-analysis
  publication-title: Ann Behav Med
  doi: 10.1207/S15324796ABM2403_04
– start-page: 399
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib97
  article-title: Handling missing data
– volume: 70
  start-page: 157
  year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib137
  article-title: Meta-analysis of patient education interventions to increase physical activity among chronically ill adults
  publication-title: Patient Educ Couns
  doi: 10.1016/j.pec.2007.10.004
– start-page: 159
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib116
  article-title: Systematic coding
– volume: 359
  start-page: 896
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib108
  article-title: Literature searches
  publication-title: Lancet
  doi: 10.1016/S0140-6736(02)07942-4
– volume: 95
  start-page: 943
  year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib130
  article-title: Assessment of publication bias for the surgeon scientist
  publication-title: Br J Surg
  doi: 10.1002/bjs.6302
– volume: 7
  start-page: 40
  year: 2000
  ident: 10.1016/j.sapharm.2015.06.001_bib109
  article-title: Systematically searching and reviewing literature
  publication-title: Nurse Res
  doi: 10.7748/nr2000.04.7.3.40.c6120
– volume: 26
  start-page: 322
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib127
  article-title: Research methods: managing primary study quality in meta-analyses
  publication-title: Res Nurs Health
  doi: 10.1002/nur.10092
– year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib31
– volume: 287
  start-page: 2829
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib104
  article-title: Association between time interval to publication and statistical significance
  publication-title: J Am Med Assoc
  doi: 10.1001/jama.287.21.2829
– year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib7
– volume: 60
  start-page: 2593
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib27
  article-title: Glycemic control and medication compliance in diabetic patients in a pharmacist-managed clinic in Hong Kong
  publication-title: Am J Health Syst Pharm
  doi: 10.1093/ajhp/60.24.2593
– volume: 1
  start-page: 1265
  year: 1976
  ident: 10.1016/j.sapharm.2015.06.001_bib22
  article-title: Improvement of medication compliance in uncontrolled hypertension
  publication-title: Lancet
  doi: 10.1016/S0140-6736(76)91737-2
– volume: 16
  start-page: 1109
  year: 2000
  ident: 10.1016/j.sapharm.2015.06.001_bib101
  article-title: What should be included in meta-analyses? An exploration of methodological issues using the ISPOT meta-analyses
  publication-title: Int J Technol Assess Health Care
  doi: 10.1017/S0266462300103150
– volume: 34
  start-page: 598
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib141
  article-title: Practical and analytic issues in the electronic assessment of adherence
  publication-title: West J Nurs Res
  doi: 10.1177/0193945911427153
– start-page: 177
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib115
  article-title: Evaluating coding decisions
– year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib52
– volume: 13
  start-page: 57
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib37
  article-title: Results of a pilot intervention trial to improve antiretroviral adherence among HIV-positive patients
  publication-title: J Assoc Nurses AIDS Care
  doi: 10.1177/1055329002238026
– volume: 4
  start-page: 20
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib128
  article-title: Publication bias in situ
  publication-title: BMC Med Res Methodol
  doi: 10.1186/1471-2288-4-20
– volume: 10
  start-page: 493
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib61
  article-title: Impact of an educational intervention for secondary prevention of myocardial infarction on Medicaid drug use and cost
  publication-title: Am J Manag Care
– volume: 333
  start-page: 15
  year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib3
  article-title: A meta-analysis of the association between adherence to drug therapy and mortality
  publication-title: Br Med J
  doi: 10.1136/bmj.38875.675486.55
– volume: 4
  start-page: 1091
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib14
  article-title: Feasibility of motivational interviewing delivered by a glaucoma educator to improve medication adherence
  publication-title: Clin Ophthalmol
  doi: 10.2147/OPTH.S12765
– volume: 25
  start-page: 1090
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib72
  article-title: Physician effectiveness in interventions to improve cardiovascular medication adherence: a systematic review
  publication-title: J Gen Intern Med
  doi: 10.1007/s11606-010-1387-9
– volume: 25
  start-page: 470
  year: 1999
  ident: 10.1016/j.sapharm.2015.06.001_bib87
  article-title: Assessing “best evidence”: issues in grading the quality of studies for systematic reviews
  publication-title: Jt Comm J Qual Improv
  doi: 10.1016/S1070-3241(16)30461-8
– volume: 47
  start-page: 826
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib68
  article-title: Physician communication and patient adherence to treatment: a meta-analysis
  publication-title: Med Care
  doi: 10.1097/MLR.0b013e31819a5acc
– start-page: CD005025
  issue: 9
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib70
  article-title: Reminder packaging for improving adherence to self-administered long-term medications
  publication-title: Cochrane Database Syst Rev
– volume: 6
  start-page: 113
  year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib38
  article-title: Results of an antiretroviral adherence intervention: STAR (Staying Healthy: Taking Antiretrovirals Regularly)
  publication-title: J Int Assoc Physicians AIDS Care
  doi: 10.1177/1545109707301243
– start-page: CD006580
  issue: 2
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib77
  article-title: Culture-specific programs for children and adults from minority groups who have asthma
  publication-title: Cochrane Database Syst Rev
– volume: 1997
  start-page: 284
  year: 1997
  ident: 10.1016/j.sapharm.2015.06.001_bib131
  article-title: Systematic review on the basis of methodological criteria
  publication-title: Physiotherapy
  doi: 10.1016/S0031-9406(05)66175-5
– volume: 20
  start-page: 359
  year: 2006
  ident: 10.1016/j.sapharm.2015.06.001_bib15
  article-title: Supporting medication adherence in renal transplantation (SMART): a pilot RCT to improve adherence to immunosuppressive regimens
  publication-title: Clin Transplant
  doi: 10.1111/j.1399-0012.2006.00493.x
– volume: 14
  start-page: 753
  year: 1985
  ident: 10.1016/j.sapharm.2015.06.001_bib64
  article-title: Clinical trials of patient education for chronic conditions: a comparative meta-analysis of intervention types
  publication-title: Prev Med
  doi: 10.1016/0091-7435(85)90070-2
– volume: 36
  start-page: 1138
  year: 1998
  ident: 10.1016/j.sapharm.2015.06.001_bib66
  article-title: Effectiveness of interventions to improve patient compliance: a meta-analysis
  publication-title: Med Care
  doi: 10.1097/00005650-199808000-00004
– volume: 287
  start-page: 2772
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib99
  article-title: Problems with indexing and citation of articles with group authorship
  publication-title: J Am Med Assoc
  doi: 10.1001/jama.287.21.2772
– volume: 69
  start-page: 239
  year: 2014
  ident: 10.1016/j.sapharm.2015.06.001_bib135
  article-title: Cultural relevance in medication adherence interventions with underrepresented adults: systematic review and meta-analysis of outcomes
  publication-title: Prev Med
  doi: 10.1016/j.ypmed.2014.10.021
– start-page: 435
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib89
  article-title: Publication bias
– volume: 6
  start-page: 29
  year: 1984
  ident: 10.1016/j.sapharm.2015.06.001_bib21
  article-title: Application of Orem's theoretical constructs to self-care medication behaviors in the elderly
  publication-title: ANS Adv Nurs Sci
  doi: 10.1097/00012272-198404000-00008
– year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib17
– volume: 23
  start-page: 38
  year: 2014
  ident: 10.1016/j.sapharm.2015.06.001_bib62
  article-title: Medication adherence study looks at types of interventions
  publication-title: Manag Care
– volume: 11
  start-page: 79
  year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib113
  article-title: Methodology for dealing with duplicate study effects in a meta-analysis
  publication-title: Organ Res Methods
  doi: 10.1177/1094428106296638
– volume: 7
  start-page: 44
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib74
  article-title: Antiretroviral adherence interventions: translating research findings to the real world clinic
  publication-title: Curr HIV/AIDS Rep
  doi: 10.1007/s11904-009-0037-5
– volume: 25
  start-page: 646
  year: 2005
  ident: 10.1016/j.sapharm.2015.06.001_bib124
  article-title: The interpretation of random-effects meta-analysis in decision models
  publication-title: Med Decis Making
  doi: 10.1177/0272989X05282643
– volume: 25
  start-page: 864
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib47
  article-title: Taking immunosuppressive medications effectively (TIMELink): a pilot randomized controlled trial in adult kidney transplant recipients
  publication-title: Clin Transpl
  doi: 10.1111/j.1399-0012.2010.01358.x
– volume: 24
  start-page: 236
  year: 2001
  ident: 10.1016/j.sapharm.2015.06.001_bib117
  article-title: The way in which intervention studies have “personality” and why it is important to meta-analysis
  publication-title: Eval Health Prof
  doi: 10.1177/016327870102400302
– volume: 10
  start-page: 179
  year: 1989
  ident: 10.1016/j.sapharm.2015.06.001_bib112
  article-title: Influences on the outcomes of literature searches for integrative research reviews
  publication-title: Knowledge
  doi: 10.1177/107554708901000301
– volume: 3
  year: 1999
  ident: 10.1016/j.sapharm.2015.06.001_bib133
  article-title: Assessing the quality of reports of randomised trials: implications for the conduct of meta-analyses
  publication-title: Health Technol Assess
  doi: 10.3310/hta3120
– volume: 19
  start-page: 745
  year: 2005
  ident: 10.1016/j.sapharm.2015.06.001_bib55
  article-title: Effects of a treatment adherence enhancement program on health literacy, patient-provider relationships, and adherence to HAART among low-income HIV-positive Spanish-speaking Latinos
  publication-title: AIDS Patient Care STDS
  doi: 10.1089/apc.2005.19.745
– volume: 116
  start-page: 2286
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib41
  article-title: Interventions improve poor adherence with once daily glaucoma medications in electronically monitored patients
  publication-title: Ophthalmology
  doi: 10.1016/j.ophtha.2009.05.026
– volume: 60
  start-page: 657
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib65
  article-title: Meta-analysis of trials of interventions to improve medication adherence
  publication-title: Am J Health Syst Pharm
  doi: 10.1093/ajhp/60.7.657
– volume: 14
  start-page: 515
  year: 2005
  ident: 10.1016/j.sapharm.2015.06.001_bib129
  article-title: Outcome selection bias in meta-analysis
  publication-title: Stat Methods Med Res
  doi: 10.1191/0962280205sm415oa
– volume: 38
  start-page: 19
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib28
  article-title: Approach to antihypertensive adherence: a feasibility study on the use of student health coaches for uninsured hypertensive adults
  publication-title: Behav Med
  doi: 10.1080/08964289.2011.651174
– volume: 11
  start-page: 275
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib26
  article-title: Support groups and treatment adherence in a geriatric outpatient clinic
  publication-title: J Clin Psychol Med Settings
  doi: 10.1023/B:JOCS.0000045347.69924.77
– volume: 44
  start-page: 964
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib78
  article-title: Medication adherence in people of culturally and linguistically diverse backgrounds: a meta-analysis
  publication-title: Ann Pharmacother
  doi: 10.1345/aph.1M572
– volume: 22
  start-page: 1
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib103
  article-title: When A. Rose is not A. Rose: the vagaries of author searching
  publication-title: Med Ref Serv Q
  doi: 10.1300/J115v22n04_01
– volume: 10
  start-page: 101
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib10
  article-title: The effect of pharmacist intervention and patient education on lipid-lowering medication compliance and plasma cholesterol levels
  publication-title: Can J Clin Pharmacol
– volume: 105
  start-page: 1308
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib18
  article-title: A study of a multi-level intervention to improve non-adherence in difficult to control asthma
  publication-title: Respir Med
  doi: 10.1016/j.rmed.2011.03.019
– volume: 52
  start-page: 816
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib73
  article-title: Intervention toolbox to promote immunosuppressant therapy adherence in adult renal transplant recipients
  publication-title: J Am Pharm Assoc (2003)
  doi: 10.1331/JAPhA.2012.11083
– volume: 25
  start-page: 303
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib25
  article-title: Brief behavioral self-regulation counseling for HIV treatment adherence delivered by cell phone: an initial test of concept trial
  publication-title: AIDS Patient Care STDS
  doi: 10.1089/apc.2010.0367
– volume: 116
  start-page: 177
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib23
  article-title: A pilot randomized clinical trial of two medication adherence and drug use interventions for HIV+ crack cocaine users
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2010.12.016
– volume: 120
  start-page: 713
  year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib71
  article-title: Fixed-dose combinations improve medication compliance: a meta-analysis
  publication-title: Am J Med
  doi: 10.1016/j.amjmed.2006.08.033
– year: 1985
  ident: 10.1016/j.sapharm.2015.06.001_bib120
– volume: 356
  start-page: 1228
  year: 2000
  ident: 10.1016/j.sapharm.2015.06.001_bib92
  article-title: Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses?
  publication-title: Lancet
  doi: 10.1016/S0140-6736(00)02786-0
– year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib8
– volume: 43
  start-page: 1165
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib40
  article-title: Effect of a warfarin adherence aid on anticoagulation control in an inner-city anticoagulation clinic population
  publication-title: Ann Pharmacother
  doi: 10.1345/aph.1L707
– start-page: 129
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib134
  article-title: Judging the quality of primary research
– volume: 43
  start-page: 62
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib33
  article-title: A culturally adapted telecommunication system to improve physical activity, diet quality, and medication adherence among hypertensive African–Americans: a randomized controlled trial
  publication-title: Ann Behav Med
  doi: 10.1007/s12160-011-9319-4
– year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib2
– volume: 2
  start-page: 103
  year: 1992
  ident: 10.1016/j.sapharm.2015.06.001_bib140
  article-title: Compliance aids—do they work?
  publication-title: Drugs Aging
  doi: 10.2165/00002512-199202020-00004
– volume: 10
  start-page: 166
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib20
  article-title: A nursing intervention for the quality use of medicines by elderly community clients
  publication-title: Int J Nurs Pract
  doi: 10.1111/j.1440-172X.2004.00476.x
– volume: 47
  start-page: 32
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib39
  article-title: Two pharmacy interventions to improve refill persistence for chronic disease medications: a randomized, controlled trial
  publication-title: Med Care
  doi: 10.1097/MLR.0b013e3181808c17
– volume: 25
  start-page: 470
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib46
  article-title: Randomized pilot study of a behavioral feedback intervention to improve medication adherence in older adults with hypertension
  publication-title: J Cardiovasc Nurs
  doi: 10.1097/JCN.0b013e3181d5f9c5
– volume: 10
  start-page: 19
  year: 2008
  ident: 10.1016/j.sapharm.2015.06.001_bib5
  article-title: Recognizing and improving patient nonadherence to statin therapy
  publication-title: Curr Atheroscler Rep
  doi: 10.1007/s11883-008-0004-4
– volume: 12
  start-page: 399
  year: 2000
  ident: 10.1016/j.sapharm.2015.06.001_bib32
  article-title: Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive men
  publication-title: AIDS Care
  doi: 10.1080/09540120050123792
– year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib59
– volume: 7
  start-page: 105
  year: 2002
  ident: 10.1016/j.sapharm.2015.06.001_bib119
  article-title: Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs
  publication-title: Psychol Methods
  doi: 10.1037/1082-989X.7.1.105
– volume: 34
  start-page: 578
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib142
  article-title: Accuracy of measures of medication adherence in a cholesterol-lowering regimen
  publication-title: West J Nurs Res
  doi: 10.1177/0193945912439251
– volume: 20
  start-page: 41
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib16
  article-title: A cost-consequences analysis of an adherence focused pharmacist-led medication review service
  publication-title: Int J Pharm Pract
  doi: 10.1111/j.2042-7174.2011.00161.x
– volume: 23
  start-page: 220
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib43
  article-title: An individualized intervention to foster optimal antiretroviral treatment-taking behavior among persons living with HIV: a pilot randomized controlled trial
  publication-title: J Assoc Nurses AIDS Care
  doi: 10.1016/j.jana.2011.04.003
– volume: 282
  start-page: 1054
  year: 1999
  ident: 10.1016/j.sapharm.2015.06.001_bib132
  article-title: The hazards of scoring the quality of clinical trials for meta-analysis
  publication-title: J Am Med Assoc
  doi: 10.1001/jama.282.11.1054
– volume: 88
  start-page: 54
  year: 2007
  ident: 10.1016/j.sapharm.2015.06.001_bib51
  article-title: Voucher reinforcement improves medication adherence in HIV-positive methadone patients: a randomized trial
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2006.09.019
– volume: 37
  start-page: 261
  year: 1995
  ident: 10.1016/j.sapharm.2015.06.001_bib58
  article-title: Adherence to zidovudine (AZT) among HIV-infected methadone patients: a pilot study of supervised therapy and dispensing compared to usual care
  publication-title: Drug Alcohol Depend
  doi: 10.1016/0376-8716(94)01080-5
– volume: 182
  start-page: 447
  year: 2010
  ident: 10.1016/j.sapharm.2015.06.001_bib57
  article-title: A cluster randomized controlled trial to evaluate an ambulatory primary care management program for patients with dyslipidemia: the TEAM study
  publication-title: Can Med Assoc J
  doi: 10.1503/cmaj.090533
– year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib82
– volume: 38
  start-page: 1617
  year: 2004
  ident: 10.1016/j.sapharm.2015.06.001_bib75
  article-title: Meta-analysis of interventions for medication adherence to antihypertensives
  publication-title: Ann Pharmacother
  doi: 10.1345/aph.1D268
– start-page: 73
  year: 2009
  ident: 10.1016/j.sapharm.2015.06.001_bib102
  article-title: Using reference databases
– volume: 101
  start-page: 751
  year: 2011
  ident: 10.1016/j.sapharm.2015.06.001_bib138
  article-title: Interventions to increase physical activity among healthy adults: meta-analysis of outcomes
  publication-title: Am J Public Health
  doi: 10.2105/AJPH.2010.194381
– volume: 16
  start-page: 3
  year: 2005
  ident: 10.1016/j.sapharm.2015.06.001_bib24
  article-title: Nurse-delivered antiretroviral treatment adherence intervention for people with low literacy skills and living with HIV/AIDS
  publication-title: J Assoc Nurses AIDS Care
  doi: 10.1016/j.jana.2005.07.001
– volume: 60
  start-page: 1123
  year: 2003
  ident: 10.1016/j.sapharm.2015.06.001_bib53
  article-title: Improving primary care in rural Alabama with a pharmacy initiative
  publication-title: Am J Health Syst Pharm
  doi: 10.1093/ajhp/60.11.1123
– volume: 89
  start-page: 346
  year: 2001
  ident: 10.1016/j.sapharm.2015.06.001_bib105
  article-title: Evidence-based practice: extending the search to find material for the systematic review
  publication-title: Bull Med Libr Assoc
– volume: 130
  start-page: 1252
  year: 2012
  ident: 10.1016/j.sapharm.2015.06.001_bib19
  article-title: Impact of a health communication intervention to improve glaucoma treatment adherence: results of the interactive study to increase glaucoma adherence to treatment trial
  publication-title: Arch Ophthalmol
  doi: 10.1001/archophthalmol.2012.1607
– volume: 39
  start-page: 1151
  year: 2001
  ident: 10.1016/j.sapharm.2015.06.001_bib50
  article-title: Two strategies to increase adherence to HIV antiretroviral medication: life-Steps and medication monitoring
  publication-title: Behav Res Ther
  doi: 10.1016/S0005-7967(00)00091-7
SSID ssj0037014
Score 2.3739169
SecondaryResourceType review_article
Snippet Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication...
SourceID pubmedcentral
proquest
pubmed
crossref
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 218
SubjectTerms Clinical Trials as Topic
Humans
Intervention
Medication Adherence
Meta-analysis
Systematic review
Title Medication adherence interventions that target subjects with adherence problems: Systematic review and meta-analysis
URI https://dx.doi.org/10.1016/j.sapharm.2015.06.001
https://www.ncbi.nlm.nih.gov/pubmed/26164400
https://www.proquest.com/docview/1762962626
https://pubmed.ncbi.nlm.nih.gov/PMC4679728
Volume 12
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NT9swFLcQu-yCBtugGyBPmjjh1k3cONkNVUPdF6oGSNwsf6pFW6hIeuDC3z6_2EnbTQhphyhKYkuO37Pfe_bv_YzQRyVTzrXhhDtuCfMBAFHpUBFtDB2a3DuwBSQ4_7jIJtfs683oZguN21wYgFXGuT_M6c1sHd8MYm8OFvP54BKMvbeH4NI0h2ZDBjvjoOX9xw7mkXLa8HtDYQKlV1k8g9t-JRdAEA0Ir1E_bEs8ZZ_-9T__hlGu2aXzV2gnOpT4LLR5F23Zcg-dTAMj9cMpvlolWFWn-ARPV1zVD69RHTZqQDpYmlnI_cPzNSBkheuZrHFAjONqqWDhpsKwfrtWI55LU33Clx01NA5pMViWBv-2tSQyEqC8Qdfnn6_GExIPYiB6lPKaKJ0qfzlmqPTjWRZKMeekdx4TJlPtHM-UpoXWTOrcGcp9XJ1YakcqZ5o7nb5F2-VdaQ8QNtrZTFEnbZawXGZ5BnxCyTDVRjpObQ-xtvuFjizlcFjGL9HC0W5FlJoAqYkAy-uhfldtEWg6nquQt7IVG_omvCl5ruqHVheEH4uwwSJLe7esxND_SeEjxCTrof2gG11rfKTqXU9Ke4hvaE1XAHi-N7-U81nD9-1tWcGT_N3_N_k9eumfsoCdO0Tb9f3SHnlnqlbHzWg5Ri_Oxj-_T-H-5dvk4g93UCej
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB7R5dBeKvpkoaWuVHHCu97EiZPeEAItBVZILBI3y0_tojasmuyBf4-9dvbRqkLqIZfEIzme8TzsmW8AvkmRMqY0w8wyg6kLALBMBxIrrclAF86BLX2B89UoH97SH3fZ3RactLUwPq0y6v6g0xfaOr7px9Xsz6bT_o039s4eepdm0TT7BWx7dKqsA9vH5xfDUauQU0YWEN9-PPYEq0Ke_n2vFjOPEe2TvLJeuJn4l4n62wX9M5NyzTSd7cDr6FOi4zDtN7BlqrdweB1AqR-P0HhVY1UfoUN0vYKrfnwHTbir8QxCQk9C-R-aruVC1qiZiAaFpHFUz6U_u6mRP8Jdo4itaerv6GaJDo1CZQwSlUa_TCOwiBgo7-H27HR8MsSxFwNWWcoaLFUq3WOpJsJtaVFKSa0Vzn9MqEiVtSyXipRKUaEKqwlzoXViiMlkQRWzKv0AneqhMruAtLIml8QKkye0EHmRe0ihZJAqLSwjpgu0XX6uIlC575fxk7cZafc8co17rvGQmdeF3pJsFpA6niMoWt7yDZHjzpo8R_q1lQXutqO_YxGVeZjXfOD-pHRBYpJ34WOQjeVsXLDqvE9CusA2pGY5wEN9b36pppMF5LczZyVLir3_n_IXeDkcX13yy_PRxT68cl_ykEr3CTrN77n57HyrRh7EvfMELRkovw
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Medication+adherence+interventions+that+target+subjects+with+adherence+problems%3A+Systematic+review+and+meta-analysis&rft.jtitle=Research+in+social+and+administrative+pharmacy&rft.au=Conn%2C+Vicki+S&rft.au=Ruppar%2C+Todd+M&rft.au=Enriquez%2C+Maithe&rft.au=Cooper%2C+Pam&rft.date=2016-03-01&rft.issn=1934-8150&rft.eissn=1934-8150&rft.volume=12&rft.issue=2&rft.spage=218&rft_id=info:doi/10.1016%2Fj.sapharm.2015.06.001&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1551-7411&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1551-7411&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1551-7411&client=summon