Inhibitory Effects of Myriocin on Non-Enzymatic Glycation of Bovine Serum Albumin

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 20; p. 6995
• Main Authors: He, Libo, Liu, Yang, Xu, Junling, Li, Jingjing, Cheng, Guohua, Cai, Jiaxiu, Dang, Jinye, Yu, Meng, Wang, Weiyan, Duan, Wei, Liu, Ke
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2022; MDPI
• Subjects: Albumin; Alzheimer's disease; Amino acids; BSA; computational simulations; Diabetes; Drugs; Fluorescence; Glucose; Hydrogen; Ligands; Metabolites; Myriocin; non-enzymatic glycation; Proteins; spectroscopic techniques; United States; Maryland; China

Advanced glycation end products (AGEs) are the compounds produced by non-enzymatic glycation of proteins, which are involved in diabetic-related complications. To investigate the potential anti-glycation activity of Myriocin (Myr), a fungal metabolite of Cordyceps, the effect of Myr on the formation...