Decision making after 50 days of simulated weightlessness
By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function ta...
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| Published in | Brain research Vol. 1280; pp. 84 - 89 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Amsterdam
Elsevier B.V
14.07.2009
Elsevier |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0006-8993 1872-6240 1872-6240 |
| DOI | 10.1016/j.brainres.2009.05.022 |
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| Abstract | By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21–45 years) selected to undergo 60 days of 6° head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest (
n
=
13) or on the 51st day of bed rest (
n
=
12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. |
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| AbstractList | By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21-45 years) selected to undergo 60 days of 6 degrees head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest (n=13) or on the 51st day of bed rest (n=12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21–45 years) selected to undergo 60 days of 6° head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest ( n = 13) or on the 51st day of bed rest ( n = 12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21-45 years) selected to undergo 60 days of 6 super(o) head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest (n=13) or on the 51st day of bed rest (n=12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. AbstractBy restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21–45 years) selected to undergo 60 days of 6° head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest ( n= 13) or on the 51st day of bed rest ( n= 12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21-45 years) selected to undergo 60 days of 6 degrees head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest (n=13) or on the 51st day of bed rest (n=12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved.By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest. The Iowa Gambling Task, a card game measuring real-life decision making processes, was administered to 25 healthy males (aged 21-45 years) selected to undergo 60 days of 6 degrees head-down tilt bed rest for the 2nd Berlin BedRest Study (BBR2-2). Testing was conducted either 6 days before beginning bed rest (n=13) or on the 51st day of bed rest (n=12). The task performance scores of subjects tested before bed rest were not significantly different from those tested during bed rest. However, subjects tested during bed rest failed to adapt their card selection strategy as the Iowa Gambling Task progressed. This was unlike the subjects tested before bed rest, who switched between decks on consecutive card selections less frequently in latter stages of the task. An influence of prolonged bed rest on decision making could have implications for the planning of human spaceflights to Mars, or for any circumstance in which adequate physical activity levels are not achieved. |
| Author | Felsenberg, Dieter Belavy, Daniel L. Gunga, Hanns-Christian Lipnicki, Darren M. |
| Author_xml | – sequence: 1 givenname: Darren M. surname: Lipnicki fullname: Lipnicki, Darren M. email: darrenlipnicki@hotmail.com organization: Center for Space Medicine Berlin, Charité Medical University Berlin, Germany – sequence: 2 givenname: Hanns-Christian surname: Gunga fullname: Gunga, Hanns-Christian organization: Center for Space Medicine Berlin, Charité Medical University Berlin, Germany – sequence: 3 givenname: Daniel L. surname: Belavy fullname: Belavy, Daniel L. organization: Center for Muscle and Bone Research, Charité Medical University Berlin, Germany – sequence: 4 givenname: Dieter surname: Felsenberg fullname: Felsenberg, Dieter organization: Center for Muscle and Bone Research, Charité Medical University Berlin, Germany |
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| Cites_doi | 10.1016/S0167-8760(03)00073-4 10.1016/0010-0277(94)90018-3 10.1093/brain/123.11.2189 10.1080/13803390500507196 10.1002/hbm.20202 10.1093/gerona/61.11.1166 10.1073/pnas.0400266101 10.1016/j.paid.2006.11.004 10.1152/japplphysiol.00751.2002 10.1212/01.wnl.0000225180.27833.c1 10.1016/j.cogbrainres.2005.03.003 10.2466/pms.103.2.307-317 10.1111/j.1365-2869.2006.00487.x 10.1016/j.neuropsychologia.2008.02.002 10.1111/1469-8986.2004.00179.x 10.1002/1529-0131(200109)44:9<2125::AID-ART365>3.0.CO;2-1 10.1017/S1355617706060802 10.1007/s11065-007-9040-z 10.1046/j.1528-1157.2001.042007912.x 10.1007/s00421-004-1067-8 10.1007/s00421-007-0474-z 10.1016/j.autneu.2004.01.001 10.1111/1467-9280.t01-1-01430 10.1038/nrn2298 10.1007/s00421-004-1208-0 10.1007/s00421-008-0869-5 |
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| Keywords | Executive function Cognition Iowa Gambling Task Physical activity Bed rest Spaceflight Physical exercise Human Decision making Neuropsychological test Psychometrics Weightlessness Space flight Rest Simulation Iowa Gambling Test |
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| Title | Decision making after 50 days of simulated weightlessness |
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