Fluorescent glycoprobes: a sweet addition for improved sensing

• Published in: Chemical communications (Cambridge, England) Vol. 53; no. 1; pp. 82 - 9
• Main Authors: He, Xiao-Peng, Zang, Yi, James, Tony D, Li, Jia, Chen, Guo-Rong, Xie, Juan
• Format: Journal Article
• Language: English
• Published: England 2017
• Subjects: Biocompatibility; Carbohydrates; Carbohydrates - chemistry; chemical compounds; chemical reactions; Fluorescence; fluorescent dyes; Fluorescent Dyes - analysis; Fluorescent Dyes - chemistry; image analysis; Imaging; ions; Ions - analysis; Molecular Imaging; precision medicine; Proteins - analysis; Receptors; Small Molecule Libraries - analysis; Small Molecule Libraries - chemistry; Solubility; Sweets; tissues; Toxicity; water solubility

The development of small-molecule fluorescent probes for the detection of ions and biomacromolecules and for cellular and in vivo imaging has been a very active research area. Nevertheless, many problems exist for traditional probes including their poor water solubility, toxicity and the inability t...