Abnormal dynamic functional connectivity and brain states in Alzheimer's diseases: functional near-infrared spectroscopy study

• Published in: Neurophotonics (Print) Vol. 6; no. 2; p. 025010
• Main Authors: Niu, Haijing, Zhu, Zhaojun, Wang, Mengjing, Li, Xuanyu, Yuan, Zhen, Sun, Yu, Han, Ying
• Format: Journal Article
• Language: English
• Published: United States S P I E - International Society for 01.04.2019; Society of Photo-Optical Instrumentation Engineers
• Subjects: Alzheimer's disease; Brain; Brain mapping; Cerebrum; Cognitive ability; Dementia; Dementia disorders; Hemoglobin; Information processing; Infrared spectroscopy; Memory; Nervous system diseases; Neural networks; Neurodegenerative diseases; Neuroimaging; Neuropsychology; Physiology; Research Papers; Signal to noise ratio; Spectrum analysis; Beijing China; China; sliding-window; k-means clustering; resting state; functional connectivity; Alzheimer’s disease; brain network

Communication within the brain is highly dynamic. Alzheimer's disease (AD) exhibits dynamic progression corresponding to a decline in memory and cognition. However, little is known of whether brain dynamics are disrupted in AD and its prodromal stage, mild cognitive impairment (MCI). For our st...