Expressions of NeuroD and GAP43 as diagnostic markers for olfactory neuroblastoma

• Published in: Auris, nasus, larynx Vol. 50; no. 3; pp. 358 - 364
• Main Authors: Furukawa, Tatsuya, Tatehara, Shun, Teshima, Masanori, Shinomiya, Hirotaka, Inokuchi, Go, Komatsu, Masato, Hara, Shigeo, Zen, Yoh, Nibu, Ken-ichi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2023
• Subjects: Carcinoma, Neuroendocrine - pathology; Esthesioneuroblastoma, Olfactory - pathology; GAP-43 Protein - metabolism; GAP43; Humans; Nasal Cavity - pathology; NeuroD; Nose Neoplasms - pathology; Olfactory Marker Protein; Olfactory neuroblastoma; Olfactory neuroepithelium; Otolaryngology; Small round cell tumor; Olfactory neuroepithelium; NeuroD; Small round cell tumor; GAP43; Olfactory neuroblastoma

Olfactory neuroblastoma (ONB) is often difficult to pathologically distinguish from other small round cell tumors (SRCTs) arising in the nasal cavities. Although there are several diagnostic markers used for differential diagnosis of ONB, these molecules are also expressed in various neuronal derive...