MRI assessment of the thigh musculature in dermatomyositis and healthy subjects using diffusion tensor imaging, intravoxel incoherent motion and dynamic DTI

• Published in: European radiology Vol. 28; no. 12; pp. 5304 - 5315
• Main Authors: Sigmund, E. E., Baete, S. H., Luo, T., Patel, K., Wang, D., Rossi, I., Duarte, A., Bruno, M., Mossa, D., Femia, A., Ramachandran, S., Stoffel, D., Babb, J. S., Franks, A. G., Bencardino, J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2018; Springer Nature B.V
• Subjects: Adult; Aged; Correlation analysis; Covariance; Debilitation; Dermatomyositis; Dermatomyositis - diagnosis; Dermatomyositis - physiopathology; Diagnostic Radiology; Diffusion; Diffusion Tensor Imaging - methods; Exercise - physiology; Female; Humans; Imaging; Inflammation; Informed consent; Internal Medicine; Interventional Radiology; Magnetic resonance imaging; Male; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - physiopathology; Muscles; Musculoskeletal; Myopathy; Neuroradiology; Patients; Quadriceps muscle; Radiology; Reproducibility of Results; Spatial heterogeneity; Thigh; Ultrasound; Variance analysis; Young Adult; Exercise; Magnetic resonance imaging; Skeletal muscle; Dermatomyositis; Diffusion tensor imaging

Introduction Dermatomyositis (DM) is an idiopathic inflammatory myopathy involving severe debilitation in need of diagnostics. We evaluated the proximal lower extremity musculature with diffusion tensor imaging (DTI), intravoxel incoherent motion (IVIM) and dynamic DTI in DM patients and controls an...