A general method to quantify ligand-driven oligomerization from fluorescence-based images - Stoneman, Michael R.; Biener, Gabriel; Ward, Richard J.; Pediani, John D.; Badu, Dammar; Eis, Annie; Popa, Ionel; Milligan, Graeme; Raicu, Valerică (Nature methods, 2019)
Keywords: 631/1647/328/1978; 631/1647/328/2057; 631/1647/527/1819; Bioinformatics; Biological Microscopy; Biological Techniques; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Brief Communication; Drug delivery; Drug screening; Epidermal growth factor; ErbB Receptors - chemistry; ErbB Receptors - metabolism; Fluorescence; Growth factors; High-throughput screening; Humans; Image Processing, Computer-Assisted - methods; Life Sciences; Ligands; Membrane proteins; Methods; Microscopy, Confocal; Monomers; Oligomerization; Oligomers; Protein Binding; Protein interaction; Protein Interaction Domains and Motifs; Protein Multimerization; Protein-protein interactions; Proteins; Proteomics; Receptors, G-Protein-Coupled - metabolism; Receptors, Gastrointestinal Hormone - metabolism; Secretin; Signal Transduction; Spectrometry; Spectrometry, Fluorescence; Variation