Quantitative Complexity Theory (QCT) in Integrative Analysis of Cardiovascular Hemodynamic Response to Posture Change

The explanation of physiological mechanisms involved in adaptation of the cardiovascular system to intrinsic and environmental demands is crucial for both basic science and clinical research. Computational algorithms integrating multivariable data that comprehensively depict complex mechanisms of ca...

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Published inLife (Basel, Switzerland) Vol. 13; no. 3; p. 632
Main Authors Krzesiński, Paweł, Marczyk, Jacek, Wolszczak, Bartosz, Gielerak, Grzegorz Gerard, Accardi, Francesco
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 24.02.2023
MDPI
Subjects
Algorithms
Analysis
Blood pressure
Cardiovascular diseases
Cardiovascular system
Case Report
complexity
Complexity theory
Computer applications
Diagnosis
Evaluation
Fainting
Heart rate
Hemodynamic monitoring
Hemodynamic responses
Hemodynamics
impedance cardiography
Medical research
Medicine, Experimental
Physiological aspects
Posture
Risk factors
Syncope
Italy
Germany
complexity
cardiovascular system
syncope
impedance cardiography
hemodynamics
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Abstract The explanation of physiological mechanisms involved in adaptation of the cardiovascular system to intrinsic and environmental demands is crucial for both basic science and clinical research. Computational algorithms integrating multivariable data that comprehensively depict complex mechanisms of cardiovascular reactivity are currently being intensively researched. Quantitative Complexity Theory (QCT) provides quantitative and holistic information on the state of multi-functional dynamic systems. The present paper aimed to describe the application of QCT in an integrative analysis of the cardiovascular hemodynamic response to posture change. Three subjects that underwent head-up tilt testing under beat-by-beat hemodynamic monitoring (impedance cardiography) were discussed in relation to the complexity trends calculated using QCT software. Complexity has been shown to be a sensitive marker of a cardiovascular hemodynamic response to orthostatic stress and vasodilator administration, and its increase has preceded changes in standard cardiovascular parameters. Complexity profiling has provided a detailed assessment of individual hemodynamic patterns of syncope. Different stimuli and complexity settings produce results of different clinical usability.
AbstractList The explanation of physiological mechanisms involved in adaptation of the cardiovascular system to intrinsic and environmental demands is crucial for both basic science and clinical research. Computational algorithms integrating multivariable data that comprehensively depict complex mechanisms of cardiovascular reactivity are currently being intensively researched. Quantitative Complexity Theory (QCT) provides quantitative and holistic information on the state of multi-functional dynamic systems. The present paper aimed to describe the application of QCT in an integrative analysis of the cardiovascular hemodynamic response to posture change. Three subjects that underwent head-up tilt testing under beat-by-beat hemodynamic monitoring (impedance cardiography) were discussed in relation to the complexity trends calculated using QCT software. Complexity has been shown to be a sensitive marker of a cardiovascular hemodynamic response to orthostatic stress and vasodilator administration, and its increase has preceded changes in standard cardiovascular parameters. Complexity profiling has provided a detailed assessment of individual hemodynamic patterns of syncope. Different stimuli and complexity settings produce results of different clinical usability.
The explanation of physiological mechanisms involved in adaptation of the cardiovascular system to intrinsic and environmental demands is crucial for both basic science and clinical research. Computational algorithms integrating multivariable data that comprehensively depict complex mechanisms of cardiovascular reactivity are currently being intensively researched. Quantitative Complexity Theory (QCT) provides quantitative and holistic information on the state of multi-functional dynamic systems. The present paper aimed to describe the application of QCT in an integrative analysis of the cardiovascular hemodynamic response to posture change. Three subjects that underwent head-up tilt testing under beat-by-beat hemodynamic monitoring (impedance cardiography) were discussed in relation to the complexity trends calculated using QCT software. Complexity has been shown to be a sensitive marker of a cardiovascular hemodynamic response to orthostatic stress and vasodilator administration, and its increase has preceded changes in standard cardiovascular parameters. Complexity profiling has provided a detailed assessment of individual hemodynamic patterns of syncope. Different stimuli and complexity settings produce results of different clinical usability.The explanation of physiological mechanisms involved in adaptation of the cardiovascular system to intrinsic and environmental demands is crucial for both basic science and clinical research. Computational algorithms integrating multivariable data that comprehensively depict complex mechanisms of cardiovascular reactivity are currently being intensively researched. Quantitative Complexity Theory (QCT) provides quantitative and holistic information on the state of multi-functional dynamic systems. The present paper aimed to describe the application of QCT in an integrative analysis of the cardiovascular hemodynamic response to posture change. Three subjects that underwent head-up tilt testing under beat-by-beat hemodynamic monitoring (impedance cardiography) were discussed in relation to the complexity trends calculated using QCT software. Complexity has been shown to be a sensitive marker of a cardiovascular hemodynamic response to orthostatic stress and vasodilator administration, and its increase has preceded changes in standard cardiovascular parameters. Complexity profiling has provided a detailed assessment of individual hemodynamic patterns of syncope. Different stimuli and complexity settings produce results of different clinical usability.
Audience Academic
Author Krzesiński, Paweł
Gielerak, Grzegorz Gerard
Wolszczak, Bartosz
Accardi, Francesco
Marczyk, Jacek
AuthorAffiliation 2 Ontonix s.r.l., 22100 Como, Italy
3 Boston Scientific S.p.A., 20134 Milano, Italy
1 Departament of Cardiology and Internal Diseases, Military Institute of Medicine, 04-141 Warsaw, Poland
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Cites_doi 10.1007/s10439-013-0879-2
10.1111/j.1542-474X.2010.00384.x
10.3390/jcm8030300
10.1115/1.4001886
10.1111/j.1469-8986.1997.tb02140.x
10.1097/00126097-200502000-00005
10.1007/BF02344724
10.1007/s10439-021-02841-9
10.1080/03091900500442855
10.1088/0967-3334/28/2/007
10.1113/jphysiol.2011.224998
10.3390/biology10101029
10.2196/11606
10.7712/100016.2254.10164
10.1053/eupc.2000.0125
10.2337/diacare.8.5.491
10.3390/s18072387
10.1371/journal.pone.0077357
10.1053/eupc.1999.0064
10.1016/j.ijcard.2012.03.115
10.3390/e20120976
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Issue 3
Keywords complexity
cardiovascular system
syncope
impedance cardiography
hemodynamics
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References Gielerak (ref_4) 2009; 67
Singh (ref_8) 2006; 30
Schang (ref_22) 2007; 28
Mereu (ref_23) 2013; 167
ref_14
ref_13
Fu (ref_25) 2012; 590
Goubergrits (ref_27) 2013; 41
ref_12
ref_11
ref_10
Antonuccio (ref_28) 2021; 49
Morbiducci (ref_26) 2010; 132
ref_16
Berntson (ref_5) 1997; 34
Li (ref_30) 2019; 7
Ewing (ref_1) 1985; 8
ref_24
ref_21
Dudek (ref_2) 2009; 26
Cybulski (ref_3) 2014; 10
Marczyk (ref_17) 2021; 23
Agner (ref_6) 2005; 10
ref_29
Molon (ref_15) 2010; 15
ref_9
Bernstein (ref_19) 2005; 43
Brignole (ref_20) 2000; 2
ref_7
Bartoletti (ref_18) 2000; 2
References_xml – volume: 41
  start-page: 2575
  year: 2013
  ident: ref_27
  article-title: The impact of MRI-based inflow for the hemodynamic evaluation of aortic coarctation
  publication-title: Ann. Biomed Eng.
  doi: 10.1007/s10439-013-0879-2
– volume: 10
  start-page: 1078
  year: 2014
  ident: ref_3
  article-title: Early hemodynamic response to the tilt test in patients with syncope
  publication-title: Arch. Med. Sci.
– volume: 15
  start-page: 301
  year: 2010
  ident: ref_15
  article-title: Baseline heart rate variability predicts clinical events in heart failure patients implanted with cardiac resynchronization therapy: Validation by means of related complexity index
  publication-title: Ann. Noninvasive Electrocardiol.
  doi: 10.1111/j.1542-474X.2010.00384.x
– volume: 23
  start-page: 8882498
  year: 2021
  ident: ref_17
  article-title: Quantitative Complexity Theory Used in the Prediction of Head-Up Tilt Testing Outcome
  publication-title: Cardiol. Res. Pract.
– ident: ref_7
  doi: 10.3390/jcm8030300
– volume: 132
  start-page: 091005
  year: 2010
  ident: ref_26
  article-title: Outflow conditions for image-based hemodynamic models of the carotid bifurcation: Implications for indicators of abnormal flow
  publication-title: J. Biomech. Eng.
  doi: 10.1115/1.4001886
– volume: 34
  start-page: 623
  year: 1997
  ident: ref_5
  article-title: Heart rate variability: Origins, methods, and interpretive caveats
  publication-title: Psychophysiology
  doi: 10.1111/j.1469-8986.1997.tb02140.x
– volume: 10
  start-page: 19
  year: 2005
  ident: ref_6
  article-title: Reproducibility of heart rate variability, blood pressure variability and baroreceptor sensitivityduring rest and head-up tilt
  publication-title: Blood Press Monit.
  doi: 10.1097/00126097-200502000-00005
– ident: ref_11
– volume: 43
  start-page: 443
  year: 2005
  ident: ref_19
  article-title: Stroke volume equation for impedance cardiography
  publication-title: Med. Biol. Eng. Comput.
  doi: 10.1007/BF02344724
– ident: ref_16
– volume: 67
  start-page: 65
  year: 2009
  ident: ref_4
  article-title: Impedance cardiography—A modern tool for monitoring therapy of cardiovascular diseases
  publication-title: Kardiol. Pol.
– ident: ref_14
– volume: 49
  start-page: 3494
  year: 2021
  ident: ref_28
  article-title: Effects of Uncertainty of Outlet Boundary Conditions in a Patient-Specific Case of Aortic Coarctation
  publication-title: Ann. Biomed. Eng.
  doi: 10.1007/s10439-021-02841-9
– volume: 30
  start-page: 145
  year: 2006
  ident: ref_8
  article-title: Spectral evaluation of aging effects on blood pressure and heart rate variations in healthy subjects
  publication-title: J. Med. Eng. Technol.
  doi: 10.1080/03091900500442855
– volume: 28
  start-page: 185
  year: 2007
  ident: ref_22
  article-title: Early prediction of unexplained syncope by support vector machines
  publication-title: Physiol. Meas.
  doi: 10.1088/0967-3334/28/2/007
– ident: ref_12
– volume: 590
  start-page: 1839
  year: 2012
  ident: ref_25
  article-title: Cardiac output and sympathetic vasoconstrictor responses during upright tilt to presyncope in healthy humans
  publication-title: J. Physiol.
  doi: 10.1113/jphysiol.2011.224998
– ident: ref_24
  doi: 10.3390/biology10101029
– volume: 7
  start-page: e11606
  year: 2019
  ident: ref_30
  article-title: The Current State of Mobile Phone Apps for Monitoring Heart Rate, Heart Rate Variability, and Atrial Fibrillation: Narrative Review
  publication-title: JMIR Mhealth. Uhealth.
  doi: 10.2196/11606
– ident: ref_29
  doi: 10.7712/100016.2254.10164
– ident: ref_13
– volume: 2
  start-page: 339
  year: 2000
  ident: ref_18
  article-title: ‘The Italian Protocol’: A simplified head-up tilt testing potentiated with oral nitroglycerin to assess patients with unexplained syncope
  publication-title: Europace
  doi: 10.1053/eupc.2000.0125
– volume: 8
  start-page: 491
  year: 1985
  ident: ref_1
  article-title: The value of cardiovascular autonomic function tests: 10 years’ experience in diabetes
  publication-title: Diabetes Care
  doi: 10.2337/diacare.8.5.491
– volume: 26
  start-page: 114
  year: 2009
  ident: ref_2
  article-title: Recommendations on the use of innovative medical technologies in cardiology and cardiac surgery and solutions leading to increased availability for Polish patients
  publication-title: Cardiol. J.
– ident: ref_10
  doi: 10.3390/s18072387
– ident: ref_9
  doi: 10.1371/journal.pone.0077357
– volume: 2
  start-page: 66
  year: 2000
  ident: ref_20
  article-title: New classification of haemodynamics of vasovagal syncope: Beyond the VASIS classification. Analysis of the pre-syncopal phase of the tilt test without and with nitroglycerin challenge. Vasovagal Syncope International Study
  publication-title: Europace
  doi: 10.1053/eupc.1999.0064
– volume: 167
  start-page: 1170
  year: 2013
  ident: ref_23
  article-title: Heart rate/blood pressure ratio as predictor of neuromediated syncope
  publication-title: Int. J. Cardiol.
  doi: 10.1016/j.ijcard.2012.03.115
– ident: ref_21
  doi: 10.3390/e20120976
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StartPage 632
SubjectTerms Algorithms
Analysis
Blood pressure
Cardiovascular diseases
Cardiovascular system
Case Report
complexity
Complexity theory
Computer applications
Diagnosis
Evaluation
Fainting
Heart rate
Hemodynamic monitoring
Hemodynamic responses
Hemodynamics
impedance cardiography
Medical research
Medicine, Experimental
Physiological aspects
Posture
Risk factors
Syncope
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Title Quantitative Complexity Theory (QCT) in Integrative Analysis of Cardiovascular Hemodynamic Response to Posture Change
URI https://www.ncbi.nlm.nih.gov/pubmed/36983787
https://www.proquest.com/docview/2791669205
https://www.proquest.com/docview/2792501325
https://pubmed.ncbi.nlm.nih.gov/PMC10052206
https://doaj.org/article/b5d216dc99454c25b109e34f8cd85567
Volume 13
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