Comparison of SARS‐CoV‐2 detection from nasopharyngeal swab samples by the Roche cobas 6800 SARS‐CoV‐2 test and a laboratory‐developed real‐time RT‐PCR test

• Published in: Journal of medical virology Vol. 92; no. 9; pp. 1695 - 1698
• Main Authors: Pujadas, Elisabet, Ibeh, Nnaemeka, Hernandez, Matthew M., Waluszko, Aneta, Sidorenko, Tatyana, Flores, Vanessa, Shiffrin, Biana, Chiu, Numthip, Young‐Francois, Alicia, Nowak, Michael D., Paniz‐Mondolfi, Alberto E., Sordillo, Emilia M., Cordon‐Cardo, Carlos, Houldsworth, Jane, Gitman, Melissa R.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.09.2020; John Wiley and Sons Inc
• Subjects: Assaying; Confidence intervals; coronavirus; Coronaviruses; COVID-19; COVID-19 - diagnosis; COVID-19 - virology; Discordance; Disease control; Humans; Infections; Laboratories; Nasopharynx - virology; Polymerase chain reaction; Prevention; Reagent Kits, Diagnostic; Reproducibility of Results; Respiratory diseases; Reverse Transcriptase Polymerase Chain Reaction - instrumentation; Reverse Transcriptase Polymerase Chain Reaction - methods; Reverse transcription; RNA extraction; RNA, Viral; SARS; SARS-CoV-2 - classification; SARS-CoV-2 - genetics; SARS-CoV-2 - isolation & purification; Sensitivity and Specificity; Severe acute respiratory syndrome coronavirus 2; Short Communication; Short Communications; Statistical analysis; Statistical methods; Viral diseases; Virology; RNA extraction; SARS; coronavirus

The urgent need to implement and rapidly expand testing for severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection has led to the development of multiple assays. How these tests perform relative to one another is poorly understood. We evaluated the concordance between the Roche Diagn...