The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients

• Published in: Journal of medical virology Vol. 92; no. 6; pp. 552 - 555
• Main Authors: Li, Yan‐Chao, Bai, Wan‐Zhu, Hashikawa, Tsutomu
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2020; John Wiley and Sons Inc
• Subjects: Betacoronavirus - pathogenicity; Betacoronavirus - physiology; Brain stem; cell susceptibility; Central nervous system; Central Nervous System - physiopathology; Central Nervous System - virology; Chemoreceptors; China - epidemiology; Coronaviridae; coronavirus; Coronavirus Infections - epidemiology; Coronavirus Infections - physiopathology; Coronavirus Infections - transmission; Coronavirus Infections - virology; Coronaviruses; COVID-19; dissemination; Epidemics; Headache; Headache - diagnosis; Headache - physiopathology; Headache - virology; Health services; Homology; Humans; Invasiveness; Lung - physiopathology; Lung - virology; Lungs; Mechanoreceptors; Mechanotransduction, Cellular; Middle East respiratory syndrome; Nausea; Nausea - diagnosis; Nausea - physiopathology; Nausea - virology; nervous system; Neurological diseases; Pandemics; Pathogenesis; Patients; Pneumonia; Pneumonia, Viral - epidemiology; Pneumonia, Viral - physiopathology; Pneumonia, Viral - transmission; Pneumonia, Viral - virology; Prevention; Respiratory diseases; Respiratory failure; Respiratory Insufficiency - diagnosis; Respiratory Insufficiency - physiopathology; Respiratory Insufficiency - virology; Respiratory therapy; Respiratory tract; Review; Reviews; SARS-CoV-2; Severe acute respiratory syndrome; Severe Acute Respiratory Syndrome - epidemiology; Severe Acute Respiratory Syndrome - physiopathology; Severe Acute Respiratory Syndrome - transmission; Severe Acute Respiratory Syndrome - virology; Severe acute respiratory syndrome coronavirus 2; Severe acute respiratory syndrome-related coronavirus - pathogenicity; Severe acute respiratory syndrome-related coronavirus - physiology; Signs and symptoms; Synapses; Viral diseases; Virology; Viruses; Vomiting; Vomiting - diagnosis; Vomiting - physiopathology; Vomiting - virology; China; coronavirus; cell susceptibility; nervous system; dissemination

Following the severe acute respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV), another highly pathogenic coronavirus named SARS‐CoV‐2 (previously known as 2019‐nCoV) emerged in December 2019 in Wuhan, China, and rapidly spreads around the world. T...