Anti‐Müllerian Hormone and Antral Follicle Count Reveal a Late Impairment of Ovarian Reserve in Patients Undergoing Low‐Gonadotoxic Regimens for Hematological Malignancies

• Published in: The oncologist (Dayton, Ohio) Vol. 18; no. 12; pp. 1307 - 1314
• Main Authors: Di Paola, Rossana, Costantini, Claudio, Tecchio, Cristina, Salvagno, Gian Luca, Montemezzi, Rachele, Perandini, Alessio, Pizzolo, Giovanni, Zaffagnini, Stefano, Franchi, Massimo
• Format: Journal Article
• Language: English
• Published: Durham, NC, USA AlphaMed Press 01.12.2013
• Subjects: Adolescent; Anti-Mullerian Hormone - analysis; Anti‐Müllerian hormone; Antral follicle count; Case-Control Studies; Female; Fertility Preservation; Gynecologic Oncology; Hematologic Neoplasms - drug therapy; Hematologic Neoplasms - physiopathology; Hematologic Neoplasms - radiotherapy; Hematological malignancies; Humans; Inhibin-beta Subunits - blood; Ovarian Follicle - diagnostic imaging; Ovarian Follicle - drug effects; Ovarian Follicle - physiopathology; Ovarian Follicle - radiation effects; Ovary - diagnostic imaging; Ovary - drug effects; Ovary - physiopathology; Ovary - radiation effects; Survivors; Ultrasonography; Young Adult; Anti-Müllerian hormone; Antral follicle count; Fertility preservation; Hematological malignancies

The impact of cancer therapy on the reproductive potential of patients is increasingly recognized because survival rates of patients have clearly improved in recent years. Different fertility preservation methods, either generally accepted or still experimental, are currently available, and counseli...