Genomic characterization and phylogenetic analysis of SARS‐COV‐2 in Italy

This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) isolated from three patients involved in the first outbreak of COVID‐19 in Lombardy, Italy. Early molecular e...

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Published inJournal of medical virology Vol. 92; no. 9; pp. 1637 - 1640
Main Authors Zehender, Gianguglielmo, Lai, Alessia, Bergna, Annalisa, Meroni, Luca, Riva, Agostino, Balotta, Claudia, Tarkowski, Maciej, Gabrieli, Arianna, Bernacchia, Dario, Rusconi, Stefano, Rizzardini, Giuliano, Antinori, Spinello, Galli, Massimo
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.09.2020
John Wiley and Sons Inc
Subjects
complete genomes of SARS‐CoV‐2
Computational Biology - methods
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - virology
Epidemiology
Genome, Viral
Genomes
Genomics - methods
Humans
Italy - epidemiology
phylogenetic analysis
Phylogenetics
Phylogeny
Regression Analysis
SARS-CoV-2 - classification
SARS-CoV-2 - genetics
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Short Communication
Short Communications
Viral diseases
Virology
Italy
COVID-19
complete genomes of SARS-CoV-2
phylogenetic analysis
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Summary:This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) isolated from three patients involved in the first outbreak of COVID‐19 in Lombardy, Italy. Early molecular epidemiological tracing suggests that SARS‐CoV‐2 was present in Italy weeks before the first reported cases of infection.
Bibliography:Gianguglielmo Zehender and Alessia Lai contributed equally to this paper.
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SourceType-Scholarly Journals-1
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ISSN:0146-6615
1096-9071
1096-9071
DOI:10.1002/jmv.25794