Forty‐Year Trends in Cholangiocarcinoma Incidence in the U.S.: Intrahepatic Disease on the Rise

• Published in: The oncologist (Dayton, Ohio) Vol. 21; no. 5; pp. 594 - 599
• Main Authors: Saha, Supriya K., Zhu, Andrew X., Fuchs, Charles S., Brooks, Gabriel A.
• Format: Journal Article
• Language: English
• Published: Durham, NC, USA AlphaMed Press 01.05.2016
• Subjects: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms - epidemiology; Bile Ducts, Intrahepatic; Cancer of unknown primary; Cholangiocarcinoma - epidemiology; Epidemiology; Extrahepatic cholangiocarcinoma; Female; Hepatobiliary; Humans; Incidence; Intrahepatic cholangiocarcinoma; Male; Middle Aged; Neoplasms, Unknown Primary - epidemiology; Trend; United States - epidemiology; Trend; Extrahepatic cholangiocarcinoma; Cancer of unknown primary; Epidemiology; Intrahepatic cholangiocarcinoma; Incidence

Background. Challenges in the diagnosis and classification of cholangiocarcinoma have made it difficult to quantify the true incidence of this highly aggressive malignancy. Methods. We analyzed the Surveillance, Epidemiology, and End Results data to assess long‐term trends in the age‐standardized in...