Early phylogenetic estimate of the effective reproduction number of SARS‐CoV‐2

• Published in: Journal of medical virology Vol. 92; no. 6; pp. 675 - 679
• Main Authors: Lai, Alessia, Bergna, Annalisa, Acciarri, Carla, Galli, Massimo, Zehender, Gianguglielmo
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2020; John Wiley and Sons Inc
• Subjects: Base Sequence; Bayes Theorem; Bayesian analysis; Betacoronavirus - classification; Betacoronavirus - genetics; Betacoronavirus - isolation & purification; Betacoronavirus - pathogenicity; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronavirus Infections - transmission; Coronavirus Infections - virology; Coronaviruses; COVID-19; Epidemics; Epidemiological Monitoring; Evolution; Evolution, Molecular; evolutionary dynamics; Genome, Viral; Genomes; Humans; Infections; Influenza; Information Dissemination; Mathematical models; Models, Statistical; Open Reading Frames; Pandemics; Phylogeny; Pneumonia, Viral - diagnosis; Pneumonia, Viral - epidemiology; Pneumonia, Viral - transmission; Pneumonia, Viral - virology; Population dynamics; Reproduction; reproductive number; RNA, Viral - genetics; SARS-CoV-2; Sequence Alignment; Sequence Homology, Nucleic Acid; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Short Communication; Short Communications; Surveillance; Viral diseases; Virology; reproductive number; SARS-CoV-2; evolutionary dynamics

To reconstruct the evolutionary dynamics of the 2019 novel‐coronavirus recently causing an outbreak in Wuhan, China, 52 SARS‐CoV‐2 genomes available on 4 February 2020 at Global Initiative on Sharing All Influenza Data were analyzed. The two models used to estimate the reproduction number (coalescen...