Palmitoylation stabilizes PD-L1 to promote breast tumor growth

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Bibliographic Details
Published in	Cell research Vol. 29; no. 1; pp. 83 - 86
Main Authors	Yang, Yi, Hsu, Jung-Mao, Sun, Linlin, Chan, Li-Chuan, Li, Chia-Wei, Hsu, Jennifer L., Wei, Yongkun, Xia, Weiya, Hou, Junwei, Qiu, Yufan, Hung, Mien-Chie
Format	Journal Article
Language	English
Published	London Nature Publishing Group UK 01.01.2019 Nature Publishing Group
Subjects	13/1 13/106 631/67/1347 631/80/458 Acyltransferases - metabolism Adenocarcinoma - metabolism Adenocarcinoma - therapy Animals B7-H1 Antigen - antagonists & inhibitors B7-H1 Antigen - metabolism Biomarkers, Tumor - metabolism Biomedical and Life Sciences Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - therapy Cell Biology Cell Line, Tumor Female HEK293 Cells Humans Letter to the Editor Life Sciences Lipoylation Mice Mice, Inbred BALB C Palmitates - therapeutic use Palmitoylation PD-L1 protein Prognosis Protein Stability
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Author	Hsu, Jung-Mao Wei, Yongkun Hsu, Jennifer L. Li, Chia-Wei Hung, Mien-Chie Sun, Linlin Xia, Weiya Qiu, Yufan Chan, Li-Chuan Hou, Junwei Yang, Yi
Author_xml	– sequence: 1 givenname: Yi surname: Yang fullname: Yang, Yi organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 2 givenname: Jung-Mao surname: Hsu fullname: Hsu, Jung-Mao organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 3 givenname: Linlin surname: Sun fullname: Sun, Linlin organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Lung Cancer Institute, Tianjin Medical University General Hospital – sequence: 4 givenname: Li-Chuan surname: Chan fullname: Chan, Li-Chuan organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston – sequence: 5 givenname: Chia-Wei surname: Li fullname: Li, Chia-Wei organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 6 givenname: Jennifer L. surname: Hsu fullname: Hsu, Jennifer L. organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston – sequence: 7 givenname: Yongkun surname: Wei fullname: Wei, Yongkun organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 8 givenname: Weiya surname: Xia fullname: Xia, Weiya organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 9 givenname: Junwei surname: Hou fullname: Hou, Junwei organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center – sequence: 10 givenname: Yufan surname: Qiu fullname: Qiu, Yufan organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, The 3rd Department of Breast Cancer, China Tianjin Breast Cancer Prevention, Treatment and Research Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer – sequence: 11 givenname: Mien-Chie surname: Hung fullname: Hung, Mien-Chie email: mhung@mdanderson.org organization: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston
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SubjectTerms	13/1 13/106 631/67/1347 631/80/458 Acyltransferases - metabolism Adenocarcinoma - metabolism Adenocarcinoma - therapy Animals B7-H1 Antigen - antagonists & inhibitors B7-H1 Antigen - metabolism Biomarkers, Tumor - metabolism Biomedical and Life Sciences Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - therapy Cell Biology Cell Line, Tumor Female HEK293 Cells Humans Letter to the Editor Life Sciences Lipoylation Mice Mice, Inbred BALB C Palmitates - therapeutic use Palmitoylation PD-L1 protein Prognosis Protein Stability
Title	Palmitoylation stabilizes PD-L1 to promote breast tumor growth
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