The clinical application of metagenomic next-generation sequencing in immunocompromised patients with severe respiratory infections in the ICU - Zhao, Junjie; Sun, Yong; Tang, Jing; Guo, Kai; Wang, Kaiyu; Zhuge, Jiancheng; Fang, Honglong (Respiratory research, 2024)
Keywords: Adult; Aged; Analysis; Anti-Bacterial Agents - therapeutic use; Antibiotics; Bronchoalveolar lavage fluid; Bronchoalveolar Lavage Fluid - microbiology; Care and treatment; Comparative analysis; Development and progression; DNA sequencing; Dosage and administration; Etiology; Female; Health aspects; High-Throughput Nucleotide Sequencing - methods; Hospital patients; Humans; Immunocompromised Host; Infection; Intensive Care Units; Lung diseases; Male; Medical research; Medicine, Experimental; Metagenomic next-generation sequencing; Metagenomics - methods; Microbiology; Middle Aged; Mortality; Nucleotide sequencing; Prognosis; Respiratory Tract Infections - diagnosis; Respiratory Tract Infections - drug therapy; Respiratory Tract Infections - immunology; Respiratory Tract Infections - microbiology; Respiratory Tract Infections - mortality; Retrospective Studies; Severe respiratory infections; Severity of Illness Index; China; Bronchoalveolar lavage fluid; Metagenomic next-generation sequencing; Antibiotics; Severe respiratory infections; Etiology