Ribitol in Solution Is an Equilibrium of Asymmetric Conformations

• Published in: Molecules (Basel, Switzerland) Vol. 26; no. 18; p. 5471
• Main Authors: Ohno, Shiho, Manabe, Noriyoshi, Yamaguchi, Takumi, Uzawa, Jun, Yamaguchi, Yoshiki
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 08.09.2021; MDPI
• Subjects: Alcohol; Carbon; conformation; dynamics; Gram-positive bacteria; Hydration; Hydrogen; hydrogen bond; MD simulation; NMR; ribitol; Sugar; Vitamin B

Ribitol (C5H12O5), an acyclic sugar alcohol, is present on mammalian α-dystroglycan as a component of O-mannose glycan. In this study, we examine the conformation and dynamics of ribitol by database analysis, experiments, and computational methods. Database analysis reveals that the anti-conformatio...