Targeted lipidomics and metabolomics evaluations of cortical neuronal stress in schizophrenia

• Published in: Schizophrenia research Vol. 212; pp. 107 - 112
• Main Author: Wood, Paul L.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2019
• Subjects: N-Acetylaspartatylglutamate; N-Acetylneuraminic acid; N-Acylethanolamines; N-Acylphosphatidylethanolamines; N-Acylphosphatidylserines; N-Acyltaurines; Plasmalogens; Psychiatric/Mental Health; Schizophrenia; Sphingolipids; N-Acylethanolamines; N-Acylphosphatidylserines; N-Acyltaurines; N-Acylphosphatidylethanolamines; Schizophrenia; Sphingolipids; N-Acetylaspartatylglutamate; Plasmalogens; N-Acetylneuraminic acid

Cortical neuronal dysfunction has been proposed to underlie the psychopathology and cognitive dysfunction of schizophrenia. Previously we have reported altered sphingolipid and N-acylphosphatidylserine (NAPS) metabolism in the frontal cortex in schizophrenia. We continue to expand these investigatio...