Androgen responses to adrenocorticotropic hormone infusion among individual women with polycystic ovary syndrome

• Published in: Fertility and sterility Vol. 106; no. 5; pp. 1252 - 1257
• Main Authors: Maas, Kevin H., Chuan, Sandy, Harrison, Evan, Cook-Andersen, Heidi, Duleba, Antoni J., Chang, R. Jeffrey
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2016
• Subjects: 17-alpha-Hydroxyprogesterone - blood; 17-OHP; Academic Medical Centers; ACTH; Adrenal Cortex - drug effects; Adrenal Cortex - metabolism; Adrenal Cortex - physiopathology; Adrenal Cortex Function Tests - methods; Adrenocorticotropic Hormone - administration & dosage; Adult; androgen; Androgens - blood; Biomarkers - blood; Case-Control Studies; Chorionic Gonadotropin - administration & dosage; Cross-Sectional Studies; Female; Humans; Hydrocortisone - blood; Infusions, Intravenous; Internal Medicine; Obstetrics and Gynecology; Ovarian Function Tests - methods; Ovary - drug effects; Ovary - metabolism; Ovary - physiopathology; polycystic ovary syndrome; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - diagnosis; Polycystic Ovary Syndrome - physiopathology; Predictive Value of Tests; Time Factors; Treatment Outcome; ACTH; androgen; 17-OHP; polycystic ovary syndrome

To compare androgen responses during ACTH infusion among women with polycystic ovary syndrome (PCOS) and healthy women. Cross-sectional study. Academic medical center. Women with PCOS (n = 13) and healthy controls (n = 15). Blood samples were obtained frequently during a 6-hour dose-response ACTH in...