Uric acid excretion in healthy subjects: a nomogram to assess the mechanisms underlying purine metabolic disorders

• Published in: Metabolism, clinical and experimental Vol. 61; no. 4; pp. 512 - 518
• Main Authors: Puig, Juan G., Torres, Rosa J., de Miguel, Eugenio, Sánchez, Arantxa, Bailén, Rebeca, Banegas, José R.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.04.2012; Elsevier
• Subjects: Adult; allopurinol; Biological and medical sciences; blood serum; correlation; Creatinine - urine; Endocrinology & Metabolism; excretion; Feeding. Feeding behavior; Fundamental and applied biological sciences. Psychology; Humans; hyperuricemia; kidneys; Male; males; metabolic diseases; Metabolic Diseases - blood; Metabolic Diseases - urine; metabolism; Middle Aged; Nomograms; oral administration; patients; Purines - metabolism; RNA; Statistics, Nonparametric; uric acid; Uric Acid - blood; Uric Acid - urine; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Excretion; Metabolic disorder; Healthy subject; Etiology; Purine; Uric acid; Endocrinology; Mechanism

The reference range for urinary uric acid excretion has not been precisely defined. Different urinary variables have been proposed to determine the renal contribution to increased or decreased serum urate concentrations. We examined which urinary variable best indicates uric acid excretion over a wi...